Congenital Malformation - A Biological Accident
Journal Title: National Journal of Integrated Research in Medicine - Year 2012, Vol 3, Issue 1
Abstract
Background: Birth of live congenitally abnormal child especially at term is a great mental and social trauma to parents, family and to the society. In developed countries it is one of the main causes of infant mortality. It accounts 8-15% of peri-natal deaths and 13-16% of neonatal deaths in India. Aims & Objectives : To find out the incidence of congenital anomalies in live and still births and to find out association of major and minor anomalies to maternal demographic profile and to various obstetrics and medical parameters. Materials & Methods: This study was carried on rural based tertiary care referral hospital. All the deliveries occurred during 1st September 2004 to 30th June 2011 (81months) comprised 7053 births were enrolled. The new born were examined systematically by obstetrician and pediatrician. System wise distribution of anomalies and correlation with risk factors were analyzed. Results: Out of total 7053 deliveries, 6433 were live births and 620 were still births. Total number of congenital malformed babies were 71 (1.006%). 31 (43.66%) of the 71 malformed babies were still born and 27 (38.02%) were NND (neonatal death). It means out of 100 stillborn, 43 babies had structural malformation. Major malformation was present in 58 and minor anomalies were present in 13 fetus. Marginal Male predominance 40 (56.33 %) was noted. Central nervous system malformation was most common in live births followed by respiratory system and musculo skeletal system. 64% patients had not taken ANC (antenatal care) and in them 92% had major anomalies. 81.3% anomalies were detected by 2nd trimester USG (ultra sonography) and 18% anomalies were not detected by USG out of which 98% were minor anomalies. Conclusion: Congenital anomalies are a major cause of still births and infant mortality. Regular ANC, 2nd trimester USG for early detection and folic acid supplementation for prevention are the important factors to be considered to decrease the burden of congenital malformation. [ Phadke et al NJIRM 2011; 2(5) : 94-97].
Authors and Affiliations
Dr. Swati M. Patel, Dr. S. B Vaishnav, Dr. Kunur N. Shah, Dr. Nipa Modi, Nitin S. Raithatha, Dr. (Mrs. ) Asmita Phadke, Dr. (Mrs. ) Jayshree Kharche, Dr. Aniruddha Joshi
Keywords
Related Articles
- EP ID EP40193
- DOI -
- Views 361
- Downloads 0
The case when anatomist and surgeon Gaspare Tagliacozzi offended God. An endless clash between religion and medical ethics.
Since the early days of religious medicine, for a therapist to disobey the priests’ views was supposed to be a sin, requiring a sacrifice to the offended God. No eminence of gifts, no splendor of reputation could shelte...
Syndrome of Malnutrition-Inflammation Complex in Chronic Alcoholics
Several studies have reported elevated serum ferritin levels in patients of chronic alcohol abuse. We hypothesized that serum ferritin may be acting as a marker of acute phase reactant, reflecting the inflammatory statu...
HIV Related Stigma and Perceived Social Support of People Living With HIV: In South India
Objective: The aim of the study was to identify factors that are associated with high level of HIV related stigma and perceived social support of People Living With HIV using HIV Stigma Scale and Multidimensional Scale...
THE EFFECTS OF EXERCISE ON DENDRITIC SPINE DENSITY: IMPLICATIONS FOR EXERCISE-INDUCED MEMORY ENHANCEMENT
The purpose of this brief review was to highlight the potential mediational role of dendritic spine morphology on the exercisememory interaction. I frst start out delineating the role of dendritic spine density on episod...
Antibacterial Effects of Azadirachta indica Leaf and Bark Extracts in Clinical Isolates of Diabetic Patients
Background: Antibacterial activities of crude Azadirachta indica (neem) bark and leaf extracts were investigated in bacterial species isolated from clinical samples of diabetic individuals. Methods and Material: Nine d...