Considerations on the Lifespan from Diagnosis to Death in Alzheimer’s Disease
Journal Title: Journal of Advances in Medicine and Medical Research - Year 2016, Vol 11, Issue 11
Abstract
Background: Evolution of Alzheimer’s disease from the onset of dementia to death is estimated by different authors as lasting between a few months and 21 years. Objective: To verify whether there is an explanation for this dispersion of evolution of cases, starting only from clinical information. Methods: A number of 75 cases of patients dead between 01. Jan. 2011 and 31. Dec. 2012 were analyzed. Data on deaths was collected from the County’s Statistics Institute; other information was collected from patient charts. Results: Gender, onset age, co-morbidities and treatment do not influence the dispersion of cases. Dispersion started at less than one month from diagnosis and ended 11.42 years after diagnosis. At the age of 65, a boom in incidence of dementia symptoms as a stage of the disease was recorded. Dispersion of cases was divided into 3 evolution groups: the majority between 0-3 years, followed by 3-6 years and 6-11.42 years, as a Gaussian curve. Conclusions: 1. The age of 64-65 may be considered a high risk age and it should be monitored accordingly. 2. The question of how just was Kraepelin’s disjunction into pre-senile and senile dementias arises. In terms of evolution, according to dispersion, there are versions of the same disease or different diseases in pathogenesis depth, but similar in symptomatology.
Authors and Affiliations
Gavril Cornutiu, Oana Let-Cornutiu
Keywords
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- EP ID EP340407
- DOI 10.9734/BJMMR/2016/21800
- Views 70
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