Corneal densitometry and its correlation with anterior and posterior elevation in keratoconus
Journal Title: Guoji Yanke Zazhi - Year 2018, Vol 11, Issue 6
Abstract
AIM: To evaluate the corneal densitometry in treatment-naive patients with keratoconus and its relevance with anterior and posterior corneal elevation.<p>METHODS: Keratoconic corneas were examined using the Pentacam. Corneal densitometry was measured over a 12-mm diameter area, divided by annular concentric zones and depths, more over anterior and posterior corneal elevation was measured. Keratoconus was classified according to the topographic keratoconus classification.<p>RESULTS: A total of 152 subjects \〖72 patients with keratoconus(46 male, 26 female)and 80 healthy control subjects(50 male,30 female)\〗 were included in the study. There were significant differences in corneal densitometry values of the groups in central 2 mm keratoconus(KC)=19.62±4.17 gray scale unit(GSU), N=15.38±1.54 GSU(<i>P</i><0.0001), and in annulus of 2 to 6 mm in diameter(K=16.40±2.18 GSU, N=15.31±1.25 GSU, <i>P</i><0.0001). When densitometry values for different depths were examined, the anterior layer presented the highest value(KC=23.69±3.71 GSU, N=20.91±2.52 GSU,<i> P</i><0.0001), which was significantly higher than the values obtained in the central and posterior layer(KC=14.34±1.70 GSU, N=13.61±1.21 GSU, <i>P</i>=0.001 and KC=11.40±1.23 GSU, N=12.35±0.88, <i>P</i>=0.002 respectively). Analysis of the correlation between corneal densitometry for each layer depth(anterior, central and posterior)with posterior corneal elevation values demonstrated significant association(<i>r</i>=0.293, <i>r</i>=0.278 and <i>r</i>=0.294 respectively). The similar correlation was not found between corneal densitometry for each layer depth and anterior corneal elevation(<i>r</i>=-0.211, <i>r</i>=-0.101, <i>r</i>=0.99 respectively). In the control patients such a significant correlation between posterior/anterior corneal elevation and corneal light backscatter for each layer depth was not found.<p>CONCLUSION: The densitometry map reveals that light backscatter was higher in the central portion of the anterior keratoconic cornea. Corneal densitometry values of keratoconus patients were correlated with posterior corneal elevation in 0-2, 6-10 and 10-12 annuli and in all anterior, central and posterior layers. The densitometry level was higher in more advanced stages.
Authors and Affiliations
Nazli Taheri
Keywords
Related Articles
- EP ID EP558486
- DOI 10.3980/j.issn.1672-5123.2018.6.03
- Views 120
- Downloads 0
Secondary intraocular hypertension after vitrectomy in patients with proliferative diabetic retinopathy
AIM: To study the postoperative incidence and related factors of high intraocular pressure after vitrectomy in patients with proliferative diabetic retinopathy(PDR). <p>METHODS: Selected in February 2014 to February 2016...
Changes and effects of orthokeratology on cornea morphology
AIM:To investigate the changes and effects of orthokeratology on corneal morphology. <p>METHODS: Totally 90 patients were treated with orthokeratology from January 2015 to December 2016. They were divided into observatio...
Rural eye care practice-survey of ophthalmology resident doctors in Nigeria
AIM:To determine the factors affecting the uptake of rural practice by trainee ophthalmologists in Nigeria.<p>METHODS: This cross sectional survey was conducted among Nigerian Ophthalmology resident doctors attending an...
Efficacy of fundus photocoagulation combined with triamcinolone acetonide on diabetic retinopathy
AIM: To observe the efficacy of fundus photocoagulation combined with triamcinolone acetonide(TA)in the treatment of diabetic retinopathy(DR). <p>METHODS: The clinical data of 94 patients(112 eyes)in our hospital from Se...
Effect analysis of intermittent exotropia operation in children of different ages
AIM:To study effect of intermittent exotropia operation in children of different ages. <p>METHODS: Totally 300 cases of children who underwent intermittent exotropia surgery in our hospital from March 2015 to April 2017...