Correlation between acute coronary syndromes and gammaglutamyl transferase level
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 1
Abstract
Context: Acute coronary syndromes (ACS) result from coronary atherosclerosis, generally with superimposed coronary thrombosis which interrupts blood flow and leads to myocardial necrosis. Aims: To study the significance of measuring gammaglutamyl transferase (GGT) level in patients with acute coronary syndromes (ACS).Materials and methods: 160 Patients diagnosed with acute coronary syndromes coming within 24 hours of symptom onset were included in the study. Relevant laboratory investigations including serum GGT level and cardiac enzymes were done. ECG were taken and detail ECG changes were noted. Analysis of data: ANOVA and f – test was used for analysis of the variables taking < 0.05 as significance level. Ethical issues: The study was carried out after obtaining approval from the Institutional Ethical Committee (IEC), Regional Institute of Medical Sciences, Imphal.Results: Majority the patients had STEMI 116(72.5%) followed by NSTEMI 29(18.1%) and unstable angina15 (9.4%). In patients with STEMI, 81.2% of male had GGT level >50 IU/L (normal- 1 to 50 IU/L), and 77.4% of female had GGT level >32 IU/L (normal- 7 to 32 IU/L). In NSTEMI group, 66.7% of male patients and 45.5% of female patients and in UA group, 3(25%) male patients and 3(100%) female patients had GGT elevated more than normal, however 60% had GGT levels normal which was statistically significant (p=0.001).
Authors and Affiliations
Keisham Jaya Chanu, Dawanroy Nongpluh, S. Bhagyabati Devi, Johan Vanlalpeka
Keywords
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- EP ID EP589360
- DOI 10.9790/0853-1601063034
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