Correlation of Resistin levels with risk factors in type 2 diabetes mellitus patients with ischemic stroke
Journal Title: Medpulse International Journal of Biochemistry - Year 2019, Vol 9, Issue 3
Abstract
Background: Ischemic stroke in diabetic individuals is complex in nature with contributions from both environmental and genetic factors. Resistin links the metabolic dysregulation to atherosclerosis through selective inhibition of PKB insulin signalling and activation of MAPK pathway. Aim: To find the correlation of resistin levels with risk factors in type 2 diabetes mellitus patients with ischemic stroke. Material and Methods: Study population was grouped as Group 1: 60 unrelated Type 2 diabetic adults diagnosed with ischemic stroke and Group 2: 60 unrelated Type 2 diabetic adults without ischemic stroke and controls including 60 individuals not fitted in either group.Results: There was a significant weak positive correlation between serum resistin levels and age, waist circumference, fasting plasma glucose, lipid profile except for HDL-c levels. Significant weak negative correlation was found between serum resistin levels and HDL-c. Conclusion: Among patients with diabetes several risk factors play a role together to promote the development of ischemic stroke. Significant correlation found between serum resistin levels and age, waist circumference, fasting plasma glucose, lipid profile except for HDL-c levels.
Authors and Affiliations
T Rameswari, G Ezhil
Keywords
Related Articles
- EP ID EP521731
- DOI 10.26611/1002931
- Views 153
- Downloads 0
Awareness of BMI and life style including physical activity, food habits and personal history among first year medical students at a rural medical college setup in Kerala
Background and Objectives: Medical education is stressful throughout the course of training. The extensive amount of material knowledge to be absorbed, social isolation, pressure of examination, discrepancies between exp...
Identification and corrective actions of preanalytical errors in clinical biochemistry laboratory of a pediatric tertiary care hospital: A two year study
Objective: To identify the leading causes of preanalytical errors in clinical biochemistry laboratory and suggesting few corrections. Methods: A retrospective analysis of the records and log registers for 2016-17, for er...
Electrolyte abnormalities in chronic heart failure patients on treatment with two different drug regimens
Background: Heart failure is a complex clinical syndrome, impairing the ability of the cardiac ventricles to fill with or eject blood. Drug therapy for Chronic Heart Failure (CHF) is aimed at providing symptomatic relief...
Decreased serum adiponectin is associated with carotid atherosclerotic changes in type 2 diabetes mellitus patients
Background: Cardiovascular disease is the leading cause of death in world. The early detection of cardiovascular disease and risk identification is paramount to prevent and treat this condition. Even though many risk pre...
Study of oxidative stress and uric acid in preeclampsia
Aims: This study is aimed to evaluate malondialdehyde levels, serum uric acid levels and serum superoxide dismutase activities were evaluated i women with preeclamosia (Group I) Results: In preeclamptic group lipid perox...