Correlation of Resistin levels with risk factors in type 2 diabetes mellitus patients with ischemic stroke
Journal Title: Medpulse International Journal of Biochemistry - Year 2019, Vol 9, Issue 3
Abstract
Background: Ischemic stroke in diabetic individuals is complex in nature with contributions from both environmental and genetic factors. Resistin links the metabolic dysregulation to atherosclerosis through selective inhibition of PKB insulin signalling and activation of MAPK pathway. Aim: To find the correlation of resistin levels with risk factors in type 2 diabetes mellitus patients with ischemic stroke. Material and Methods: Study population was grouped as Group 1: 60 unrelated Type 2 diabetic adults diagnosed with ischemic stroke and Group 2: 60 unrelated Type 2 diabetic adults without ischemic stroke and controls including 60 individuals not fitted in either group.Results: There was a significant weak positive correlation between serum resistin levels and age, waist circumference, fasting plasma glucose, lipid profile except for HDL-c levels. Significant weak negative correlation was found between serum resistin levels and HDL-c. Conclusion: Among patients with diabetes several risk factors play a role together to promote the development of ischemic stroke. Significant correlation found between serum resistin levels and age, waist circumference, fasting plasma glucose, lipid profile except for HDL-c levels.
Authors and Affiliations
T Rameswari, G Ezhil
Keywords
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- EP ID EP521731
- DOI 10.26611/1002931
- Views 150
- Downloads 0
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