Crohn’s Disease: Pathophysiology, and Management
Journal Title: The Egyptian Journal of Hospital Medicine - Year 2018, Vol 70, Issue 11
Abstract
<strong>Background:</strong> The incidence of crohn’s disease reaches up to 20 per 100,000 people per year, with a median age of 30 years, and is higher in the developed world. Although the exact cause and pathophysiology is unknown, several environmental and genetic factors have been linked with higher risk or severity of the disease. <br /> <strong>Methodology:</strong> We conducted this review using a comprehensive search of MEDLINE, PubMed, and EMBASE, January 1985, through February 2017. The following search terms were used: crohn’s disease, inflammatory bowel disease, genetics of crohn’s disease, diagnosis of IBD, management crohn’s disease<em><br /> </em><strong>Aim of the study:</strong> In this review, we aim to study the pathophysiology, diagnosis and management of crohn’s disease. We will pay special attention to the newer biological drugs used in management. <br /> <strong>Conclusion:</strong> Crohn’s disease is usually managed with medical treatment, although many patients will need to undergo surgery at least once. Treatment usually aims at the induction and maintenance of a remission without the excessive use and dependence of steroids. Achieving higher quality of life is the main goal of any modality of treatment.
Authors and Affiliations
Eman Helal
Keywords
Related Articles
- EP ID EP583766
- DOI 10.12816/ejhm.2018.9407
- Views 99
- Downloads 0
Prognostic Value of Platelet to Lymphocyte Ratio in Patients with Non-Small Cell Lung Cancer
<strong>Background: </strong>The prognostic value of Platelet-to-lymphocyte ratio (PLR) in patients with non-small-cell lung cancer (NSCLC) is still indistinct. We conducted this study to assess the prognostic significan...
Assessment of Vitamin D Status In Patients With Essential Hypertension
<strong>Background: </strong>There is close relationship between Vit D deficiency and hypertension. It was found that Vit D is potent inhibitor of Renin Aldosterone Angiotensin System (RAAS) which is the main mechanism r...
Prevalence of Different Eye Diseases Excluding Refractive Errors Presented at the Outpatient Clinic in Beheira Eye Hospital
<strong>Purpose of this study </strong>was to determine the frequency and spectrum of eye disorders presenting to the eye clinic of Damnhour, Behira Eye Hospital. <strong>Introduction: </strong>Epidemiological studies pr...
Comparative Study between Hysterosalpingography, Saline Infusion Transvaginal Ultrasound and Doppler Studies in Assessment of Uterine Factor of Infertility
Background: One of the basic steps of an infertility workup is to evaluate the shape and regularity of the uterine cavity. Acquired uterine lesions, such as uterine fibroids, endometrial polyps, intrauterine adhesions, o...
Supraclavicular Brachial Plexus Nerve Block versus Patient Controlled Analgesia for Post-Operative Pain Management in Forearm Surgery
<strong>Background:</strong> supraclavicular Brachial plexus block is an excellent method for attaining optimal operating conditions for upper limb surgeries by producing complete muscular relaxation, maintaining haemody...