Cross-Sectional Study of Semen Analysis in Type 2 Diabetic Men
Journal Title: Medpulse International Journal of Physiology - Year 2019, Vol 9, Issue 1
Abstract
Background: Diabetes is an endocrine disorder with effects on various body systems. Its impact on male reproductive system has been of interest to the researchers. This cross-sectional study was done to assess the semen parameters among type 2 diabetic men attending the reproductive biology unit at our tertiary care centre. Methods: This was a cross-sectional study. Thirty diabetic males in the age group of 25 – 55 years on oral hypoglycaemic drugs for ten or more than ten years visiting reproductive biology unit of Physiology Department at the Government Medical College, Aurangabad for the evaluation of semen parameters were enrolled as cases and thirty non-diabetic fertile males having one or more than one child were enrolled as controls. Fasting and post meal blood glucose levels were evaluated. Semen sample was collected after abstinence of four days. Semen analysis was done on Biovis Computer Assisted Semen Analysis; CASA 2000.Sperm morphology was done manually after staining technique using Diff-quick method. Results were analysed statistically between the groups by applying Student ‘t’ test. Results: The Mean ± Standard Deviation (SD) value of fasting blood sugar (mg %) in diabetics and nondiabetics was 107.7 ± 27.87 and 85.73 ± 11.98 and post meal blood sugar was 159.53 ± 52.49 and 110.97 ± 13.97 respectively. Mean ± SD value of sperm concentration (million/ejaculate) was 133.14 ± 43.92 and 136 .19 ± 58.08 in diabetics and nondiabetics respectively. Mean ± SD value of sperm motility (%) was 58.17 ± 17.93 and 68 .74 ± 15.07 in diabetics and nondiabetics respectively. Mean ± SD value of normal sperm morphology (%) was 26.8 ± 12.36 and 62.00 ± 16.51 in diabetics and nondiabetics respectively. Conclusions: The study results reflect no significant difference in sperm concentration and motility among diabetic subjects on oral hypoglycaemic agents being evaluated for infertility as compared to non-diabetic fertile subjects. Sperm morphology evaluation showed significantly less percentage of normal sperms among the diabetic subjects on oral hypoglycaemic agents.
Authors and Affiliations
Ranjana C Shingne, G R Naghate, Sayeeda Afroz, Ayesha Baig
Keywords
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- EP ID EP471328
- DOI 10.26611/103912
- Views 162
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