Cutaneous granular cell tumor. Report of three cases and review of the literature
Journal Title: Nasza Dermatologia Online - Year 2012, Vol 3, Issue 1
Abstract
Granular cell tumors (GCT) are benign neoplasms of distinctive differentiation when observed by light microscopy, which are characterized by the presence of cells with abundant granular eosinophilic cytoplasm. We present three clinical cases were histological study revealed a non-encapsulated tumorous lesion formed by large cells, organized in groupings of abundant cytoplasm containing eosinophilic granules and small, centrally located nuclei. Immunohistochemical study was performed in one case and demonstrated the presence of S100. The indicated treatment was local conservative surgical excision.
Authors and Affiliations
Beatriz Di Martino Ortiz, Ana Soskin Reidman
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