Cytodiagnosis of Chondrosarcomatous Transformation in a patient with Multiple Osteochondromasq
Journal Title: Indian Journal of Pathology: Research and Practice - Year 2018, Vol 7, Issue 8
Abstract
Osteochondroma (Exostosis) is the most common benign tumor of the bone. It may occur as solitary or multiple lesions and most commonly affected age group is 11-20 years. Its common complications include cosmetic or osseous deformity, fracture, neurovascular compromise, bursa formation and malignant transformation. Latter is the most serious and feared complication occurring mostly in third to fifth decade. The risk of malignant progression is estimated to range from 1 to 25% in patients with multiple osteochondromas. In this study, we present a case of high grade chondrosarcoma which was diagnosed cytologically in a 27 year old male with multiple osteochondromas. Cytological smears were cellular showing atypical cells with marked pleomorphism in a background with chondromyxoid material. Subsequent histopathology of the lesion confirmed the diagnosis. Through this case report we wish to highlight that FNAC is very effective in confirming preoperative diagnosis of chondrosarcomatous transformation in osteochondroma.
Authors and Affiliations
Shivani Panhotra
Keywords
Related Articles
- EP ID EP529189
- DOI 10.21088/ijprp.2278.148X.7818.13
- Views 73
- Downloads 0
Ki-67 Expression in Primary Breast Carcinomas and Their Correlation Nottingham Modification of Scarff Bloom Richardson Grading System
Background: Carcinoma breast is the one of the most common causes of cancer death among women. Early diagnosis and effective treatment of the disease are immensely important. The increasing number of options for treatmen...
Cyto–Histopathological Correlation of Various Thyroid Lesions and Evaluation of the Bethesda System for Reporting Thyroid Cytopathology: A 3 Year Retrospective Study
Background: Fine Needle Aspiration Cytology (FNAC) is important for pre-operative and pre-treatment diagnosis of benign and malignant thyroid lesions, thus decreasing the incidence of unwanted surgeries. Objectives: The...
Comparative Study of Conventional Papanicolaou Smear and Cytospin Smear in Cervical Cancer Screening
Context: Cervical carcinoma is the fourth common malignancy in women worldwide and second most common in developing countries including India. Cytological screening leads to a reduction in the rate of invasive cancer of...
Prevalence of Oral Premalignant and Malignant Lesions in Tertiary Health Care Centre, Central India: A Retrospective Study
Introduction: Oral cancer is a grave health menace in the world and India being a developing nation is not an exception to it. In India, diagnosis is often made at later stages resulting in lower treatment outcomes and c...
A Clinicopathological Study and Immunohistochemical Expression of p53 in Ovarian Tumors
Background: Ovarian tumours are heterogenous neoplasms with a varied clinical, morphological and histological features. p53 overexpression has been associated with poor prognosis, poor overall survival and altered sensit...