Cytogenetic Study in Couples with Primary Infertility
Journal Title: Journal of Medical Science And clinical Research - Year 2016, Vol 4, Issue 1
Abstract
Fertility denotes the ability of a man and woman to reproduce. Conversely, infertility denotes lack of fertility, an involuntary reduction in the ability to produce children. A total of thirty three couples were studied in an attempt to find out the cytogenetic causes in primary infertility. The couples were assessed for other contributory factors like age, consanguinity, anatomical abnormalities, hormonal causes or any other medical causes. Cytogenetic analysis of the infertile couples revealed that chromosomal abnormalities were present in one of the partner in 36.36% of couples. Chromosomal abnormalities were found in 24.24% females and 12.12% males. Among the chromosomal abnormalities, numerical abnormalities were present in 18.18% couples and structural abnormalities were present in 12.12% couples. Most common among the numerical abnormalities was 47, XXY i.e 3 cases, mosaicism was seen in 3 cases (2 females and 1 male). 46, XY karyotype was found in two phenotypic females with primary infertility. Structural abnormalities were present in 12.12% of female patients.
Authors and Affiliations
Dr Rakhi More
Keywords
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