Dapagliflozin- Induced Severe Ketoacidosis Requiring Hemodialysis
Journal Title: Clinical Medical Reviews and Case Reports - Year 2016, Vol 3, Issue 12
Abstract
The availability of novel classes of medication for the treatment of type 2 Diabetes mellitus (type 2 DM) provides doctors with options to choose individualized treatments based on patient and agent characteristics beyond metformin therapy, as per current guidelines. Independent of impaired beta-cell function and insulin resistance, sodium glucose cotransporter type 2 (SGLT2) inhibitors represent a different treatment strategy for reducing plasma glucose levels and glycosylated hemoglobin concentrations by increasing urinary glucose excretion through reduced renal glucose reabsorption.
Unusual Early Aortic Valve Bioprosthesis Failure due to Fungal Infection
We report an early failure of a 19 mm mitroflow A12 aortic pericardial bioprosthetic valve. We excluded all described causes related with early bioprosthesis calcification and degeneration. Neither inflammatory cells nor...
Management of Congenital Afibrinogenemia: Report of Two Cases
Fibrinogen (Factor I) is an essential factor in the coagulation cascade. The activation of prothrombin to thrombin by Factor X is followed by the activation of fibrinogen. In turn, thrombin converts fibrinogen to fibrin,...
Acute Liver Failure Secondary to AL Amyloidosis
AL amyloidosis, the most common form of amyloidosis, involves the extracellular deposition of immunoglobulin light chain protein fibrils, usually in the setting of a plasma cell dyscrasia. Amyloid deposition can occur in...
An Asymptomatic Case of Hamartoma Located in the Trachea
Primary tumors of trachea are usually malignant (90%). Hamartomas are the most frequently seen benign lung tumors. Hamartomas are usually located peripherally but they can be present as endobronchial localization in 8-10...
Unresolved Issues concerning Inadequate Immune Response after Rabies Post-Exposure Prophylaxis in an Immunocompromised Patient
We present an immunocompromised patient with inadequate immune response to the rabies post exposure prophylaxis (PEP), and our management strategy after this inadequate response. Currently, evidence based strategy for ac...