Dapsone hypersensitivity syndrome - A case report
Journal Title: National Journal of Physiology, Pharmacy and Pharmacology - Year 2018, Vol 8, Issue 4
Abstract
Dapsone is widely used for the treatment of leprosy and other immunological and inflammatory dermatological conditions such as dermatitis herpetiformis, vesiculobullous dermatoses, and pustular psoriasis. Dapsone hypersensitivity syndrome (DHS) is a rare reaction associated with fever, skin eruptions, and internal organs involvement. We report a case of DHS who presented with fever, productive cough, dyspnea, skin rashes, and jaundice. Leukocytosis, eosinophilia, and altered liver enzymes were observed in laboratory investigations and patient improved with conservative management.
Authors and Affiliations
Selvalaxmi Gnanasegaran, Mangaiarkkarasi Adhimoolam, Srija Gopal
Keywords
Related Articles
- EP ID EP487845
- DOI 10.5455/njppp.2017.7.1042308112017
- Views 82
- Downloads 0
Evaluation of antianxiety activity of ethanolic extract of leaves of Ocimum sanctum (tulsi) in albino mice
Background: Anxiety is a normal emotional behavior, however, becomes pathological precipitating cardiovascular and psychiatric disorders when it is severe. Many allopathic drugs are available to treat anxiety disorders,...
Brainstem auditory evoked potentials in the older population
Background: The central nervous system is no exception to the effects of aging. Physiologic changes due to aging have been suggested to impair the neurotransmission in the auditory pathways. Brainstem auditory evoked pot...
Glycosylated hemoglobin as a marker of dyslipidemia in type 2 diabetes mellitus patients in a tertiary care hospital
Background: Type 2 diabetes mellitus (DM) is one of the modern pandemics. Evidence has emerged supporting the benefits of glycemic control as well as control of blood pressure and lipid levels in the prevention or delay...
Physiological cost index of different body mass index and age of an individual
Background: The energy expenditure is the amount of energy (or calories) that a person needs to carry out a physical function such as breathing, circulating blood, digesting food, or a physical movement. The method for e...
Effectiveness of video-assisted comprehensive teaching program in enhancing knowledge, improving compliance, and life coping mechanism among tuberculosis patients
Background: Tuberculosis (TB) is one of the major global health problems responsible for ill health among millions of people. In India, each year, approximately 220,000 deaths are reported due to TB. Even today, two deat...