Dentinal Tubule Occluding Effect of Potassium Nitrate in Varied Forms, Frequencies and Duration: An In vitro SEM Analysis
Journal Title: Journal of Clinical and Diagnostic Research - Year 2017, Vol 11, Issue 8
Abstract
Introduction: Dentinal hypersensitivity is an exaggerated response to non-noxious sensory stimuli (osmotic, thermal or mechanical changes). An inverse relationship between occluding open tubules and the intensity of sensitivity has been reported. Studies on the efficacy of potassium nitrate used in different forms and frequencies to occlude dentinal tubules are scarce. Aim: To evaluate, in vitro the dentinal tubule occluding effect of potassium nitrate which differ in form, frequency and duration of application. Materials and Methods: In an in vitro study, 45 extracted human maxillary and mandibular premolars were sectioned using diamond disc to obtain 90 samples which were treated with 6% citric acid and were randomly assigned to three groups: Group 1 was treated with potassium nitrate toothpaste (once and twice daily for two minutes); Group 2 with potassium nitrate mouthwash (once and twice daily for two minutes) and Group 3 served as control (distilled water). Post-treatment, the samples were immersed in distilled water. The samples were subjected to Scanning Electron Microscopy (SEM) at the end of 3, 7 and 14 days. SEM photographs were analysed based on extent of tubular occlusion. Chi-square test was applied to assess the significant difference between the groups. Results: There was detectable difference in the dentinal tubule occlusion at the end of 3rd, 7th and 14th day between three groups. When compared to the mouthwash, toothpaste yielded better results. Twice daily application for a period of two minutes each was better when compared to once daily for two minutes. Conclusion: Potassium nitrate is effective in occluding dentinal tubules when applied twice daily in toothpaste form than mouthwash form. However, randomised control trials are needed to confirm its efficacy in human subjects.
Authors and Affiliations
jESLINE MERLY JAMES, MANJUNATH P PURANIK, KR SOWMYA
Keywords
Related Articles
- EP ID EP361675
- DOI 10.7860/JCDR/2017/26442.10340
- Views 92
- Downloads 0
Subtyping of Non-Small Cell Lung Carcinomas in Bronchoscopic Biopsies: A Tertiary Care Centre Experience
ABSTRACT Introduction: The advent of promising targeted therapies against specific subtypes of Non-small Cell Lung Carcinoma (NSCLC) has made it mandatory for the pathologists to subclassify NSCLC into its subtypes, alon...
Bilateral Testicular Metastases from Occult Primary Prostate Cancer in a Young Adult: A Rare Case Report
Testicular metastases are detected incidentally in upto 4% cases after orchiectomy for Prostate Carcinoma (PCa). Most of the secondaries to testes are due to PCa, only few patients have clinically manifested metastases t...
Microfilariae of Wuchereria bancrofti in Testicular Aspirate
Present study deals with results of fine needle aspiration of both the testes in a patient with azoospermia. Surprisingly, aspiration of right testis revealed large number of microfilariae in the smears. Conversely, left...
Unilateral and Atypical Presentation of Vogt-Koyanagi-Harada Syndrome: A Case Report
A BSTRACT Vogt-Koyanagi-Harada (VKH) disease is a multisystem disorder with ocular manifestations including severe bilateral panuveitis with iridocyclitis, serous retinal detachment, diffuse choroidal swelling and optic...
The Efficacy of 311-NM Narrowband Ultraviolet B (NB-UVB) and Topical Agents or Lasers Combination Therapy versus NB-UVB Monotherapy for Vitiligo: A Systematic Review and Meta-analysis of Randomised Controlled Trials
ABSTRACT Introduction: Even though there is the availability of multiple treatment modalities for vitiligo still its treatment remains challenging. Combination therapies of Narrowband Ultraviolet B (NB-UVB) and various t...