Dermatologic Manifestations in End Stage Renal Disease Patients on Maintenance Hemodialysis
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2019, Vol 18, Issue 3
Abstract
Background: End Stage Renal Disease(ESRD) presents with an array of cutaneous manifestations. Newer changes are being described since the advent of hemodialysis, which prolongs the life expectancy, giving time for these changes to manifest. Aim: The aim of this study was to evaluate the prevalence of dermatologic problems among patients with End Stage Renal Disease (ESRD) undergoing hemodialysis. Methods: One hundred patients with ESRD on hemodialysis were examined for cutaneous changes. Results: Eighty-two per cent patients complained of some dermatologic problem. However, on examination, all patients had atleast one skin lesion attributable to ESRD. The most prevalent finding was xerosis(79%), followed by pallor(60%), pruritus(53%) and skin pigmentation(43%).other dermatologic manifestations include Kyrle’s disease (21%), fungal (30%), bacterial (13%) and viral (12%) infections; uremic frost (3%), purpura (9%), gynecomastia (1%);and dermatitis (2%). The nail changes included half and half nail (21%), koilonychia (18%), onychomycosis (19%), subungual hyperkeratosis (12%), onycholysis (10%), splinter hemorrhages (5%), Mees' lines (7%), Muehrcke's lines (5%) and Beau's lines (2%). Hair changes included sparse body hair (30%), sparse scalp hair (11%) and brittle and lusterless hair (16%). Oral changes included macroglossia with teeth markings (35%), xerostomia (31%), ulcerative stomatitis (29%), angular cheilitis (12%) and uremic breath (8%). Some rare manifestations of ESRD like uremic frost, gynecomastia and pseudo-Kaposi's sarcoma were also observed. Conclusions: ESRD is associated with a complex array of cutaneous manifestations caused either by the disease or by treatment. The commonest are xerosis and prutitus and the early recognition of dermatologic manifestations can relieve suffering and decrease morbidity.
Authors and Affiliations
R. Gandhimohan, A. Prabhakaran
Keywords
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- EP ID EP555349
- DOI 10.9790/0853-1803081015.
- Views 95
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