Detection of Mycoplasma pneumoniae and Chlamydia trachomatis in Iranian children with acute lower respiratory infections by polymerase chain reaction
Journal Title: Asian Pacific Journal of Tropical Disease - Year 2014, Vol 4, Issue 0
Abstract
Objective: To determine the frequency of Mycoplasma pneumoniae (M. pneumoniae) and Chlamydia trachomatis (C. trachomatis) in young children with community acquired pneumonia (CAP) and detect C. trachomatis in the subgroup of infants under 1 year of age in Tehran, Iran. Methods: This cross-sectional study was designed to detect M. pneumoniae from all children (<5 years of age) presenting with CAP, admitted to a tertiary care children ’s hospital affiliated with the Shaheed Beheshti University of Medical Sciences in Tehran during a period of 14 months, from November 2010 to December 2011. Nasopharyngeal and oropharyngeal swabs were collected from 102 children during the study period. Pathogens were detected using polymerase chain reaction and confirmed with real-time polymerase chain reaction. Results: Only one case of M. pneumoniae was isolated from 102 children (1%). C. trachomatis was not detected in any of the 69 infants (<1 year of age). Conclusions: According to our findings, M. pneumoniae is an uncommon cause of CAP in children under 5 years old and C. trachomatis could not be listed as causing CAP in infants in our study population. However, more studies with a larger sample size are needed to confirm this observation.
Lymphatic filariasis: knowledge, attitude and practices among inhabitants of an irrigation project community, North Central Nigeria
Objective: To ascertain the knowledge of lymphatic filariasis among inhabitants of an irrigation project community in north central Nigeria. Methods: A descriptive cross sectional study which involved 285 participants ≥≥...
Silver nanoparticles: Antibacterial activity against wound isolates & invitro cytotoxic activity on Human Caucasian colon adenocarcinoma
Objective: To synthesize the silver nanoparticles (AgNPs) using the extracts of Hypnea sp. and to investigate the antibacterial activity against Eshcherichia coli, Staphylococcus aureus and invitro cytotoxic activity on...
Histomorphological and morphometric studies of the pancreatic islet cells of diabetic rats treated with aqueous extracts of Momordica charantia (karela) fruits
Objective: To investigate the effect of aqueous extract of Momordica charantia (karela) (M. charantia) fruits on blood glucose level, pancreatic weight changes and histopathology of pancreatic changes in the streptozotoc...
Relaxation effect of marmin on guinea pig tracheal smooth muscle via NO-independent mechanisms
Objective: To investigate the relaxation mechanims of marmin on epithelium of guinea pig isolated trachea smooth muscle (TSM). Methods: The study was conducted using in vitro isolated-trachea experimental. The guinea pig...
TB-PACTS: A fresh emphatic data sharing approach
Tuberculosis (TB) is a leading dreadful tropical disease which causes 1.5 million mortalities per year and nearly one-third of all TB cases are unreported annually. Keeping in view of the therapeutic properties of mycoba...