Development of a Novel Oral Cavity Compartmental Absorption and Transit Model for Sublingual Administration: Illustration with Zolpidem

Journal Title: The AAPS Journal - Year 2015, Vol 17, Issue 3

Abstract

The online version of this article (doi:10.1208/s12248-015-9727-7) contains supplementary material, which is available to authorized users.

Authors and Affiliations

Binfeng Xia, Zhen Yang, Haiying Zhou, Viera Lukacova, Wei Zhu, Mikolaj Milewski, Filippos Kesisoglou

Keywords

Related Articles

Challenges in Development of Nanoparticle-Based Therapeutics

In recent years, nanotechnology has been increasingly applied to the area of drug development. Nanoparticle-based therapeutics can confer the ability to overcome biological barriers, effectively deliver hydrophobic drugs...

Approaches to the Development of Human Health Toxicity Values for Active Pharmaceutical Ingredients in the Environment

Management of active pharmaceutical ingredients (API) in the environment is challenging because these substances represent a large and diverse group of compounds. Advanced wastewater treatment technologies that can remov...

Cellular Uptake Mechanism of Paclitaxel Nanocrystals Determined by Confocal Imaging and Kinetic Measurement

The online version of this article (doi:10.1208/s12248-015-9774-0) contains supplementary material, which is available to authorized users.

Synergistic Antibiotic Combination Powders of Colistin and Rifampicin Provide High Aerosolization Efficiency and Moisture Protection

The online version of this article (doi:10.1208/s12248-013-9537-8) contains supplementary material, which is available to authorized users.

Prediction of Biliary Excretion in Rats and Humans Using Molecular Weight and Quantitative Structure–Pharmacokinetic Relationships

The aims were (1) to evaluate the molecular weight (MW) dependence of biliary excretion and (2) to develop quantitative structure–pharmacokinetic relationships (QSPKR) to predict biliary clearance (CLb) and perce...

Download PDF file
  • EP ID EP680949
  • DOI  10.1208/s12248-015-9727-7
  • Views 49
  • Downloads 0

How To Cite

Binfeng Xia, Zhen Yang, Haiying Zhou, Viera Lukacova, Wei Zhu, Mikolaj Milewski, Filippos Kesisoglou (2015). Development of a Novel Oral Cavity Compartmental Absorption and Transit Model for Sublingual Administration: Illustration with Zolpidem. The AAPS Journal, 17(3), -. https://europub.co.uk./articles/-A-680949