Development of a standard Preparation Procedure and Physicochemical Analysis of Simhanad Guggulu
Journal Title: International Journal of Ayurveda and Pharmaceutical Chemistry - Year 2017, Vol 0, Issue 0
Abstract
Simhanad Gugglu is a drug of choice for Amavata and according to today’s scenario Amavata is very common joint disorder worldwide. Preparation of Simhanad guggulu is not so critical but the common & efficacious pharmaceutical procedure which is described in Bhaishajya Ratnavali & Ayurvedic Formulary of India is not palatable. Therefore, present study is completed with the aim of developing standard operating procedure of Simhanad Guggulu which will be more efficacious and palatable. In Bhaishajya ratnavali patha quantity of oil is more which make it semisolid doses form. In Amavata proper dose of Castrol oil facilitate purgation and amapachana. So in the present study, it was a challenge to develop S.O.P. which will fulfill objectives of this work. Aims & Objectives: To develop standard operative procedure for preparation of Simhanad Guggulu, to improve palatability and simultaneously improving efficacy. Materials and methods: Simhanad Guggulu was prepared by three different methods given in Ayurveda classics i.e.,, Bhaishajya Ratnavali, Ayurved Sara Sangraha and Rasatantrasara and Siddhapravog Sangrah. Physicochemical analysis carried out of only one patha i.e. Ayurvedsar sangraha patha in three samples. Sample I handmade tablet, Sample II Granulation and compression tablet, Sample III marketed formulation. Results: For efficacious and palatable formulation we can modify bhaishajya ratnavali sample in soft gelatin capsule. We can prepare simhanad Guggulu in tablet form only by following Ayurved sar sangrah patha which is available in market.
Authors and Affiliations
Nalini Rameshrao Hedaoo, Ujwala Ashokrao Jadhao, Chatragun Eknathrao Lagad, Rajesh Kundalikrao Ingole
Keywords
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