Dexmedetomidine as an Anaesthetic Adjuvant in ENT Surgeries
Journal Title: Indian Journal of Anesthesia and Analgesia - Year 2018, Vol 5, Issue 11
Abstract
Context: Dexmedetomidine is an alpha 2 receptor agonist with sympatholytic, analgesic and sedative effects. This study was designed to study the anaesthetic sparing effect of dexmedetomidine and to compare the efficacy of dexmedetomidine with fentanyl. Aims: 1) to study the effect of dexmedetomidine and compare dexmedetomidine with fentanyl in patients undergoing ENT surgeries. Methods and Material: After approval from institutional ethical committee a prospective randomized controlled study was conducted in forty ASA class 1 and 2 patients posted for ENT surgeries. Patients were randomly divided into two groups. Dexmedetomidine group received a bolus dose of 1mcg/kg body weight over ten minutes followed by infusion at the rate of 0.4mcg/kg/minute. Fentanyl group patients received 2mcg/kg fentanyl five minutes before the induction. Haemodynamic parameters were measured at specific end points. The anaesthetic and analgesic requirement was noted. Statistical analysis used: Data was analysed using computer statistical software system openepi. The unpaired ttest was used for intergroup comparisons except where specified. Probability values p < 0.05 were considered significant and p < 0.001 were considered highly significant. Results: It was noted that there was no significant difference haemodynamic parameters and quality of surgical field. The average sevoflurane during the first hour of surgery was significantly lower in group D. The incidence of postoperative nausea and vomiting was significantly lower in group F. Conclusions: Dexmedetomidine used in the dose of 1mcg/kg IV bolus followed by 0.4mcg/kg/hour provides effective and well tolerated alternative to fentanyl in reducing the requirement of analgesic and anaesthetic agents.
Authors and Affiliations
Mohan Sandhya
Keywords
Related Articles
- EP ID EP549574
- DOI 10.21088/ijaa.2349.8471.51118.21
- Views 90
- Downloads 0
Comparison of Ropivacaine 0.2% Versus Bupivacaine 0.125% in Ultrasound Guided Continuous Interscalene Analgesia for Shoulder and Upper Arm Surgeries: A Randomized Prospective Study
Background and Aims: Shoulder surgery is associated with significant postoperative pain. A continuous interscalene brachial plexus block provides an excellent postoperative analgesic modality for early rehabilitation and...
Efficacy of Ketamine Gargle for Attenuating Post-Operative Sore Throat in Patient Undergoing General Anaesthesia with Endotracheal Intubation
Background and Objective: Postoperative sore throat (POST) is a common complication of general anaesthesia with endotracheal intubation that affects patient satisfaction after surgery. Postoperative sore throat following...
Comparision of Bupivacaine with and without Clonidine as for Supraclavicular Approach to Brachial Plexus Block
Introduction: The role of peripheral nerve blockade was expanded for management of post operative pain and chronic pain. Tramadol and fentanyl had been successfully used as adjuvant to local anaesthetic in brachial plexu...
Evaluation of Dexmedetomidine as an Additive to Ropivacaine for Popliteal Approach for Sciatic Nerve Block for Foot Surgeries
Introduction: Peripheral nerve blocks are used in varieties of surgical and diagnostic procedures. Various methods or approaches have been tried to prolong the duration of nerve blocks. Dexmedetomidine acts selectively o...
A Case Report of Ca. Breast Patient with Metastasis, DVT and Hypoalbuminemia Posted for Modified Radical Mastectomy Under Thoracic Epidural Anaesthesia: A Challenge for Anaesthesiologist
Modified Radical Mastectomy, the surgical procedure for carcinoma of breast is routinely performed under general anaesthesia. Patient with lung metastasis and low serum albumin are at increased risk of perioperative morb...