DIABETIC AUTONOMIC NEUROPATHY: INDEPENDENT FACTOR IN LUNG FUNCTION IMPAIRMENT
Journal Title: World Journal of Pharmaceutical Research - Year 2019, Vol 8, Issue 5
Abstract
Objective: Diabetic Autonomic Neuropathy is one of diabetes mellitus complications that might cause respiratory abnormalities and increase the rate of morbidity and mortality. The aim of the present study was to assess pulmonary functions in type 2 diabetic patients with and without diabetic autonomic neuropathy and correlate it with age, disease duration and disease control. Materials and methods: This study was conducted at Al-Mouassat University Hospital in Damascus during one year (from October 2013 to November 2014). 67 patients with type 2 diabetes mellitus were divided into two groups: with and without diabetic autonomic neuropathy. Diabetics with microangiopathy and macroangiopathy were excluded to evaluate the effect of autonomic neuropathy as an independent factor on lung functions. Results: Subjects with diabetic autonomic neuropathy showed a significant reduction in forced vital capacity (FVC) and forced expiratory volume in one second (FEV1) compared to their predicted values. Whereas, there was no significant difference in lung function parameters in patients without autonomic neuropathy compared to their predicted values. 45% of patients with autonomic neuropathy had mild degree of restrictive pulmonary disease. There was an inverse, significant correlation between glycosylated hemoglobin A1c, diabetes duration and both FVC and FEV1 values. Conclusion: 45% of Patients with type-2 diabetes and autonomic neuropathy had a restrictive respiratory defect. Glycemic levels and duration of disease are probably major determinants of lung pathology.
Authors and Affiliations
Dr. Yousser Mohammad
Keywords
Related Articles
- EP ID EP672197
- DOI -
- Views 124
- Downloads 0
CARBON SEQUESTRATION: A SOLUTION TO GLOBAL PROBLEM
Over the last 30 years there is a drastic increase of CO2 emission due to the combustion of fossil fuel and it is causing a major change in the environment such as global warming. It is assumed that this major change is...
COMPARATIVE EVALUATION OF THE FLAVONOIDS CONSTITUENTS IN SOME VERBENAEUS SPECIES CULTIVATED IN EGYPT.
Phytochemical screening of Tectona grandis (1), Verbena bipinnatifida (2), Duranta repens (3), Duranta lorentzii (4), Caryopteris incana (5), Gmelina arborea (6), Gmelina hystrix (7) and Verbena hybrida (8) plants showed...
CONCEPTUAL STUDY OF SNAKE BITE AND ITS MANAGEMENT
Snake bite is a significant health concern, especially in rural populations of tropical and subtropical countries. In India, snake bites take a heavy toll of human lives, and therefore warrant urgent attention. High mort...
QUANTUM MECHANICAL NATURE OF PAIN SENSITIVITY
Previously, we have suggested the metabolic controlling of cell hydration as a common quantum mechanical sensitive target through which different factors could modulate membrane excitability and impairment of metabolic d...
KNOWLEDGE, ATTITUDE AND PRACTICE AMONG SAUDI POPULATION OF URINARY TRACT STONES AND THEIR RADIOLOGICAL DIAGNOSTIC METHODS, SAUDI ARABIA, 2018
Background: Urolithiasis is an ordinary complication with a growing incidence and occurrence worldwide. Urinary tract stone occurs from either migrated renal calculi or urinary stasis. It can further be divided into prim...