DIABETIC FOOT ULCERS- OLD PROBLEMS, NEW TECHNOLOGIES
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 12
Abstract
BACKGROUND The term diabetes mellitus is a metabolic disorder characterised by chronic hyperglycaemia with disturbances of carbohydrate, fat and protein metabolism resulting from defects in insulin secretion, action or both. Non-traumatic amputations mostly arise from diabetes mellitus and the chances are 15 - 46 times higher in diabetics. Further, foot complications are the most frequent reason for hospitalisation in patients with diabetes mellitus, accounting for up to 25% of all admissions. Objective- To study the role of recombinant platelet derived growth factor in Wagner’s grade 2 diabetic foot ulcer. MATERIALS AND METHODS In a prospective study on 50 patients, 25 patients were undertaken in the study group (Group A) and 25 patients in the control group (Group B). Study group received PDGF gel, while the control group received Betadine dressing. Patients were followed up after every two weeks up to eight weeks. Qualitative analysis was done according to the wound size, discharge type, discharge amount, cellulitis and granulation tissue. RESULTS The platelet derived growth factor plays a significant role in the treatment and outcome of diabetic foot ulcers. The end result was significant in all the measured parameters. 24 out of 25 patients in study group attained the end result as compared to 4 out of 25 patients in control group. In study group, there was significant reduction in the size of wound at 7th week. In study group end point results were achieved in 96% cases, which included the complete closure of wound either by healing, suturing or skin grafting. CONCLUSION Recombinant platelet derived growth factor plays a significant role in treating diabetic foot ulcers.
Authors and Affiliations
Anuj Mahajan, Tejinderpal Singh, Anju Bhagtana, Aaina Malhotra
Keywords
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- EP ID EP412056
- DOI 10.14260/jemds/2018/338
- Views 84
- Downloads 0
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