Diagnosis of Amniotic Fluid Leak by Nitrazine Indicator Impregnated in Diagnostic Pantyliner: Its Specificity and Sensitivity for Detection of Premature Rupture of Membranes
Journal Title: International Journal of Medical Research Professionals - Year 2017, Vol 3, Issue 5
Abstract
Objective: To check sensitivity and specificity of nitrazine test after modifying it with a non-invasive absorbent pad used as a pantyliner impregnated with nitrazine molecule. Materials and Methods: This was a prospective cohort study conducted on 150 patients seeking medical advice in labor room of Darbhanga Medical College and Hospital. Study was done on 2 groups. Group 1 consisted of women presently with suspected leak without digital examination. Group 2 consisted of women with overt leak with digital examination. DPL was applied in both groups and results were compared with the standard speculum examination. Results: Sensitivity of DPL test was 97.22% and specificity was 83.33% PPV was 89.7% and NPV was 95.24% accuracy of the test was 91.67%. Conclusion: In the clinical challenge of diagnosing PPROM, non-invasiveness rapidity of testing and high accuracy rate of DPL test may provide a solution to the modern obstetrician.
Authors and Affiliations
Shruti Prabha, Kumudini Jha
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