“Diagnostic Use of Spot Urine Protein-Creatinine Ratio, Their Correlation in Quantification of Proteinuria in Hypertensive Pregnant Women”
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2019, Vol 18, Issue 4
Abstract
objective was to study the correlation between Protein– creatinine ratio of spot urine sample. Correlation of the values in hypertensive pregnant females Implications and correlation with clinical scenario. Patient would be selected according to criteria for gestational hypertension. blood pressure determined by mercury sphygmomanometer on two occasions at least 4 hrs apart. The sample collected would be the first morning urine sample/ midstream sample. The cut off value of P/C would be fixed determined by receiver operating characteristics (ROC) curve. Observation shows mean value of serum creatinine in normal and pregnant females whose values are 055±.0.14 mg /dl and 0.77±0.29 mg/dl.t value is 3.75 while p value is 0.03 and hence the value is significant in this case also. The level of serum creatinine in complicated pregnancy is more as compared to normal pregnancy. value of 24 hour urinary creatinine in normal pregnancy is 2.63±53,82 while in complicated pregnancy it is 1.66±35.36.The value is significant(t-value is 9.65 and p- value is 0.02) decrease in the urinary creatinine. This decrease is due to decrease in the normal functioning of the kidney. The glomerular filteration rate and renal plasma flow is decreased leading to decrease in creatinine. The parameters would be assessed and accordingly a criteria would be established to predict course of action in patients with proteinuria and gestational hypertension and an attempt would be made to determine clinical severity.
Authors and Affiliations
Dr Siddharth Kapoor, Dr. Kumar Vivek, Dr Govind J Sahay
Keywords
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- EP ID EP572180
- DOI 10.9790/0853-1804033236.
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