Diagnostic Utility of Bone Marrow Aspiration and Biopsy in Paediatric Age Group
Journal Title: International Journal of Contemporary Medical Research - Year 2016, Vol 3, Issue 8
Abstract
Introduction: Bone marrow examination required for differential diagnosis of various myelo and lymphoproliferative disorders; their prognostic classification and assessment of status during and after therapy, staging of lymphoma and marrow infiltration. Study aimed to evaluate the contribution of bone marrow aspiration and trephine biopsy to the final diagnosis. Material and methods: Two and half year study of BM trephine biopsy lesions in pediatric population (0 to 18 yrs). BM biopsy processed with H and E stain and special stains. Results: maximum cases were male s and from age group of 12- 18 yrs, fever is the most common symptom and pallor is most common sign encountered, majority cases were anemias followed by infectious disease, Leukemias and ITP. BM aspiration and BM Biopsy are complimentary to each other in 72.5% cases. Conclusion: Bone marrow Aspiration and BM Biopsy are confirmative for tissue diagnosis and plays important role is clinical diagnosis, prognosis and also to decide line of management.
Authors and Affiliations
Lalita Y. Patil, Yoganand V. Patil, Grace D’Costa, Arvind Valand
Keywords
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