Diagnostic validity of the anxiety and depression questions from the Well-Being Process Questionnaire
Journal Title: Journal of Clinical and Translational Research - Year 2018, Vol 4, Issue 2
Abstract
Background: Previous research shows that the Well-being Process Questionnaire (WPQ) has good content validity, construct validity, discriminant validity and reliability. Aims: The present research examined the diagnostic validity of the anxiety and depression questions from the WPQ by comparing them with the Hospital Anxiety and Depression scale (HADS) from which they were derived. Method: One hundred and twenty university staff members aged 20-64 participated in the study which involved an anonymous online survey. The data were used to assess the ability of single item measures, rated on a 10 point scale, to correctly identify a respondent that meets a diagnostic criteria, in this case clinical levels of depression or anxiety. Results: This analysis involved comparison with an established measure (HADS clinical cut-off) in terms of the proportion of those with the condition correctly identified as such (sensitivity) by the single items and the proportion without the condition correctly identified as such (specificity) by the single items. The results showed that a cut-off point at a score of 5 provided the best results for sensitivity and specificity in the depression and anxiety items. Sensitivity at this point was 71.4% and 86.3% for depression and anxiety respectively, while specificity was 85.4% for depression and 72.6% for anxiety. Conclusion: These findings confirm that the single item anxiety and depression questions from the WPQ can be used as an initial screening tool to identify clinical cases of anxiety and depression. Relevance for patients: This will provide a rapid method of assessment that will benefit patients and lead to more effective prevention and management.
Authors and Affiliations
Gary Williams, Andrew P Smith
Acellular porcine heart matrices: whole organ decellularization with 3D-bioscaffold & vascular preservation
Regenerative medicine, particularly decellularization-recellularization methods via whole-organ tissue engineering, has been increasingly studied due to the growing donor organ shortage. Though numerous decellularization...
Survey and critical appraisal of pharmacological agents with potential thermo-modulatory properties in the context of artificially induced hypometabolism
A reduction in body temperature can be achieved by a downward adjustment of the termoneutral zone, a process also described as anapyrexia. Pharmacological induction of anapyrexia could enable numerous applications in med...
Evidence against a role for platelet-derived molecules in liver regeneration after partial hepatectomy in humans
Background and Aim: Blood platelets have been shown to stimulate liver regeneration after partial hepatectomy in animal models and humans, but the molecular mechanisms involved are unclear. It has been proposed that grow...
The effects of trans-resveratrol on insulin resistance, inflammation, and microbiota in men with the metabolic syndrome: A pilot randomized, placebo-controlled clinical trial
Background and Aim: The metabolic syndrome (MetS) is a pathological condition comprised of abdominal obesity, insulin resistance, hypertension, and hyperlipidemia. It has become a major threat globally, resulting in rapi...
Assessment of the Wii Basic Balance Test in measuring postural deficits post-concussion
Background and Aim: To evaluate the Wii Basic Balance Test (WBBT), as a tool for detecting postural instability in athletes with concussions. Methods: Seventy-nine healthy physically active controls (NORM) (mean age 21...