Diagnostic Value of Specific Markers in the Verification of Bacterial Nature of the Inflammatory Processes in the Respiratory System
Journal Title: Актуальна інфектологія - Year 2016, Vol 3, Issue 12
Abstract
Introduction. Recently, there are accumulated more data on the role of infection as a risk factor for wheezing syndrome, bronchial asthma (BA) and its exacerbations, which often calls for differential diagnosis with such complications, as pneumonia of bacterial or viral etiology. Objective of the study: in order to improve the diagnosis of bacterial inflammations of the airways in children of all ages to explore some results of the patients’ survey. Materials and methods. Comprehensively, we have examined 279 sick children, from infancy to the preschool age. The first (I) clinical group consisted of 100 infants, who were admitted to the hospital for community-acquired bacterial pneumonia (BP). The second (II) group included 56 children with asthma, in whom we have confirmed the bacterial nature of febrile asthma attacks. The third (III) group consisted of 46 BA patients with confirmed viral nature of febrile asthma exacerbations. The fourth (IV) group included 77 infants with acute respiratory viral infection (ARVI) in the form of acute bronchitis (45 children), bronchiolitis (15 cases) and viral pneumonia (17 patients). Results and their discussion. The white blood cell count of the peripheral blood revealed in patients with BP the presence of bacterial and inflammatory process in contrast to peers with ARVI. The study of C-reactive protein concentrations in the blood serum allowed us to obtain the following results: the average content of this protein and in I clinical group was 67.26 ± 4.90 mg/l, in IV group — 22.39 ± 4.40 mg/l, in II group — 56.2 ± 2.6 mg/l and in III comparison group— 28.8 ± 2.4 mg/l (PI : II, III, IV; II : III, IV < 0.05). Conclusions. Consequently, none of the studied clinical and paraclinical markers have an independent diagnostic value in confirming bacterial inflammation.
Authors and Affiliations
O. K. Koloskova, L. A. Ivanova, T. M. Bіlous, R. I. Goncharuk
Keywords
Related Articles
- EP ID EP210163
- DOI 10.22141/2312-413x.3.12.2016.81712
- Views 69
- Downloads 0
Modern approaches to the treatment of herpetic infection in children
It is currently known 8 pathogenic herpesviruses: two types of herpes simplex virus (HSV-1, HSV-2), varicella zoster virus, Epstein-Barr virus, cytomegalovirus, HHV-6, HHV-7, and HHV-8. Herpes simplex virus type 1 and ty...
Features of the dynamics of the indicators of epidemiological surveillance for poliomyelitis in conditions of decline vaccination coverage
The article presents the results of epidemiological surveillance of acute flaccid paralysis and the level of vaccination against poliomyelitis coverage in the Zaporizhzhia region in 2012–2016.
Optimization of Topical Treatment of Acute and Chronic Tonsillitis
The paper presents the features of acute and chronic tonsillitis in children. We examined 52 patients with acute tonsillitis, they are divided into 2 groups: in the complex treatment of the first group of children we use...
Immune response of adult people living with human immunodeficiency virus to the introduction of diphtheria and tetanus toxoid (review of literature)
The increase in the number of people living with human immunodeficiency virus (PLHIV) and significant increase in their life expectancy on the background of antiretroviral therapy raises the issue of vaccination of these...
Possibility of acute intestinal food-borne infections holiatry: approach with combined pre- and probiotic
The article deals with the study of the efficiency of using contemporary combined prebiotic and probiotic as the component of the holiatry in patients with acute intestinal infection. Clinical and microbiological efficie...