Diffuse large B-cell lymphoma of thyroid gland: A case report
Journal Title: Medpulse International Journal of Medicine - Year 2019, Vol 9, Issue 1
Abstract
Background: Primar lymphoma is an uncommon malignancy of the thyroid, comprising 0.6 to 5 percent of thyroid cancers in most series. Primary thyroid lymphomas (PTL) occur most commonly in elderly women and are commonly of B-cell origin. Here, we report a case of 74-year-old obese female, a known case of lymphocytic thyroiditis, diagnosed as thyroid lymphoma (diffuse large B-cell) on fine needle aspiration and confirmed histopathogically and immunohistochemically. She presented with a sudden increase in thyroid swelling. Fine needle aspiration performed showed highly cellular smears comprising predominantly of the monomorphic population of medium to large sized lymphoid cells with high nuclear/cytoplasmic ratio and scant cytoplasm. A possibility of thyroid lymphoma possibly diffuse large B-cell lymphoma was suggested which was later confirmed on biopsy. Fine needle aspiration provides an easy mode for diagnosing large cell lymphoma like diffuse large B-cell. Hence, an early diagnosis is possible for a timely intervention.
Authors and Affiliations
Bala Koteswara Rao P, Jayshree C Awalekar, Ajinkye Nashte, Rahul Surve, Harshad .
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