Disparate effects of anti-TNF-α therapies on measures of disease activity and mediators of endothelial damage in ankylosing spondylitis.
Journal Title: Pharmacological Reports - Year 2013, Vol 65, Issue 4
Abstract
Asymmetric dimethylarginine (ADMA) is associated with endothelial injury. Increased ADMA levels are found in rheumatoid arthritis (RA) and ankylosing spondylitis (AS). We set out to assess the ADMA and symmetric dimethylarginine (SDMA) levels in AS, RA, and healthy controls, and in the anti-TNF treated patients with active AS.
Authors and Affiliations
Mariusz Korkosz, Jerzy Gąsowski, Andrzej Surdacki, Piotr Leszczyński, Katarzyna Pawlak-Buś, Sławomir Jeka, Maciej Siedlar, Tomasz Grodzicki
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