DO PLATELET INDICES PLAY A ROLE WITH RESPECT TO PLATELET COUNT AND INFECTIONS?
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 44
Abstract
BACKGROUND Platelet an essential constituent of blood plays an important role in coagulation, thrombosis, inflammation and maintains the integrity of vascular endothelial cells. Platelet indices like Plateletcrit (PCT), Mean Platelet Volume (MPV), Platelet Distribution Width (PDW) and Platelet Large Cell Ratio (P-LCR) are a group of derived platelet parameters obtained as a part of automatic complete blood count. Various infections and metabolic disorders cause variations in the platelet counts and platelet indices. This study aims to summarise the potential role of platelets and platelet indices as risk markers for early screening of infections. MATERIALS AND METHODS This is a descriptive comparative study. The present study included 103 cases and they were subtyped into four groups, i.e. tuberculosis, dengue, malaria and chronic liver disease. Platelet indices in different infections were obtained. RESULTS PDW was normal in dengue, malaria and chronic liver disease, but decreased in tuberculosis. MPV was normal in malaria, dengue and chronic liver disease, but MPV was low in tuberculosis. P-LCR was increased in dengue and malaria, decreased in tuberculosis and normal in chronic liver disease. CONCLUSION Platelet indices have been valuable indicators of illness severity and effective predictors of clinical outcomes. Platelet indices could be easily measured from routine blood examination that is inexpensive and repeatable. This provides a convenient stratification tool in infections.
Authors and Affiliations
Rachana Kiran Koppalkar, Purnima S. Rao, Sandhya I, Prithal G
Keywords
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- EP ID EP549255
- DOI 10.14260/jemds/2018/1061
- Views 83
- Downloads 0
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