Do pregnancy rates differ with intra-uterine insemination when different combinations of semen analysis parameters are abnormal?
Journal Title: UNKNOWN - Year 2018, Vol 19, Issue 2
Abstract
Objective: To evaluate the relationship of one or a combination of semen analysis parameter results on insemination outcomes. Material and Methods: A retrospective analysis was performed to evaluate the effect on pregnancy rates in relation to one or more abnormal semen analysis parameters based on the 2010 World Health Organization semen analysis guidelines. Results: Nine hundred eighty-one couples underwent 2231 intrauterine insemination cycles at the Stanford Fertility and Reproductive Medicine Center. In our study, the pregnancy rates ranged from 11-25% when an individual or combined semen analysis parameters were analyzed. Similar pregnancy rates were found when one, two, and in most cases three parameters were abnormal. When a single parameter was abnormal among volume, concentration, and motility, pregnancy rates were mainly unaffected. There was the exception of total sperm count where pregnancy rates were diminished when counts were below 39 million (p=0.04). Conclusion: Clearly, total sperm in the specimen and not the concentration of sperm per milliliter was the critical factor for predicting pregnancy. Therefore, a reorganization of semen analysis reports should be done emphasizing the total amount of sperm present and de-emphasizing concentration of sperm.
Authors and Affiliations
Anita Kuriya, Chioma Agbo, Michael H. Dahan
Keywords
Related Articles
- EP ID EP364996
- DOI 10.4274/jtgga.2017.0082
- Views 75
- Downloads 0
JTGGA CME/CPD CREDITING
.
Impact of energy devices on the post-operative systemic immune response in women undergoing total laparoscopic hysterectomy for benign disease of the uterus
Objective: Laparoscopic surgery is associated with reduced surgical stress response, lesser post- operative immune function, and consequent early recovery compared with conventional open surgery. There is a lack of evide...
DHEA supplementation improves endometrial HOXA-10 mRNA expression in poor responders
Objective The study was planned to investigate whether DHEA supplementation had an impact on endometrial receptivity in women who were poor responders (POR). Materials and Methods Twenty-eight POR women who were undergo...
Congress report of the 23rd AGE annual meeting from 26th - 28th April 2018 in Hamburg
The Study Group of Gynecological Endoscopy (AGE) has a growing number of members each year. This is an acknowledgment as well as a challenge for the study group. The challenges were faced in the form of exemplary coopera...
Detrimental effect of Hypericum perforatum on ovarian functions
Objective: Hypericum perforatum is widely used for depression and distress treatment as an over-the-counter plant at any age. This study investigated the safety of H. perforatum on ovarian function and infertility. Mater...