Does Sickle Cell Disease Protect Against Diabetes Mellitus? Cross-sectional study

Journal Title: Sultan Qaboos University Medical Journal - Year 2015, Vol 15, Issue 1

Abstract

Objectives: Te co-existence of diabetes mellitus (DM) and sickle cell disease (SCD) is rare. Tis study aimed to explore whether SCD patients have the same DM prevalence as the general population in a country with a high prevalence of DM. Methods: Tis cross-sectional study included all SCD adult patients admitted to Salmaniya Medical Complex, Bahrain, between 2003 and 2010 (n = 2,204). A random sample (n = 520) was taken to establish the prevalence of DM. Laboratory records were examined to determine the presence of DM. Results: Tere were 376 SCD patients with complete records; of these, 24 (6.4%) had DM. Te age- and sex-standardised prevalence of DM was 8.3%. Conclusion: While the prevalence of DM in SCD patients in Bahrain was high, it was lower than expected in this population. SCD may have a protective effect towards DM development. However, the impact of these two conditions on vascular diseases suggest a need for screening and aggressive treatment in this population.

Authors and Affiliations

Ali A. Mohamed| School of Medicine, Royal College of Surgeons in Ireland Medical University of Bahrain, Busaiteen, Bahrain, Fathia Al-Qurashi| Department of Haematology, Royal Albert Edward Infrmary, Wrightington, Wigan & Leigh NHS Foundation Trust, UK, David L. Whitford| Department of Family & Community Medicine

Keywords

Related Articles

Early versus Late Parenteral Nutrition in Very Low Birthweight Neonates A retrospective study from Oman

Te aim of this study was to compare the biochemical parameters, weight gain, osteopenia and phosphate supplementation in very low birth weight (VLBW) neonates receiving early versus late parenteral nutrition (EPN versu...

Spontaneous Resolution of Fetal and Neonatal Ascites after Birth

Fetal ascites is an uncommon abnormality usually reported in relation to non- immunological causes. Te prospect for fetal and neonatal mortality is high, particularly when the ascites develops before 24 weeks of gestat...

The Controversies of Hyponatraemia in Hypothyroidism Weighing the evidence

Hyponatraemia is a common electrolyte disturbance, with moderate (serum sodium: 125–129 mmol/L) to severe (serum sodium: ≤125 mmol/L) forms of the disease occurring in 4–15% of hospitalised patients. While it is...

Attitudes of Saudi Arabian Undergraduate Medical Students towards Health Research

Objectives: Tis study aimed to evaluate attitudes, perceptions and perceived barriers towards health research among Saudi Arabian undergraduate medical students. Methods: Tis cross-sectional study took place between Au...

Download PDF file
  • EP ID EP14540
  • DOI -
  • Views 344
  • Downloads 11

How To Cite

Ali A. Mohamed, Fathia Al-Qurashi, David L. Whitford (2015). Does Sickle Cell Disease Protect Against Diabetes Mellitus? Cross-sectional study. Sultan Qaboos University Medical Journal, 15(1), 116-119. https://europub.co.uk./articles/-A-14540