Dogs susceptibility to rabies after a vaccination campaign in endemic areas of Peru.

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Dogs susceptibility to rabies after a vaccination campaign in endemic areas of Peru.

Journal Title: Revista Peruana de Medicina Experimental y Salud Publica - Year 2007, Vol 24, Issue 1

Abstract

[i][b]Objective: [/b][/i]To determine the level of immune response after a mass vaccination campaign against rabies in two areas which presented cases of canine rabies in the last years. [i][b]Materials and methods:[/b][/i] A serologic survey was carried out in 101 and 199 dogs located respectively, in the cities of Tambo Grande (Piura) and Juliaca (Puno) and a rabies serum mouse neutralization test was perform to measure neutralizing antibodies (≥ 0,5 UI/mL) according to area of study, vaccination antecedents, age and sex of the dog. [i][b]Results:[/b][/i] After three months of the rabies campaign 32% of all dogs were properly protected, 66% had vaccination antecedents and only 44% of the vaccinated dogs had antibodies (> 0,1UI/mL). A greater protection against rabies was found in Juliaca than in Tambo Grande in vaccinated dogs (51 vs 34%, p<0,05). Dogs older than a year old were better protected than dogs under a year old (p<0,01), but non relation was found between sex and protection (p>0,05). [b][i]Conclusions:[/i][/b] This study found that there is a poor immune response against rabies in the districts of Tambo Grande, and Juliaca, making them very susceptible to develop dog rabies outbreaks.

Authors and Affiliations

Ricardo López, Albina Díaz, Edgar Condori

Keywords

EP ID EP123740
DOI -
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