Drug Prescribing Pattern & Adverse Drug Effects Of Anti Glaucoma Medication for Primary Glaucoma at Tertiary Care Hospital
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 11
Abstract
Objective: The study aims to analyse the Drug prescribing pattern and Adverse drug effects of Antiglaucoma medication for Primary Glaucoma in a Tertiary care teaching hospital. Methods: It is an Observational Study done on 100 patients of Primary Glaucoma presenting in Out patients department of Glaucoma unit at Sarojini Devi Eye Hospital. The study was carried for a period of 6 months. Details regarding patients demographic data, drugs prescribed and any adverse effects to Antiglaucoma medication were noted. Results: Over a period of 6 months it was found that out of 100 cases of Primary Glaucoma 50 were males and 50 were females. There were more than 50% of PACG cases reported than POAG. Out of 100 cases Combination therapy was prescribed in 87 patients and Monotherapy in 13 patients. Among these combination therapy, 72 patients were on Concomitant therapy and remaining were on FDC . Dorzolamide & Timolol FDC were commonly prescribed followed by Brimonidine & Timolol and Timolol+Travoprost. Among monotherapy Beta blockers were commonly prescribed followed by Prostaglandin analogues & Carbonic Anhydrase Inhibitors. In total of 100 cases 32 patients reported ADRs. Itching was the most common ADR. Most of ADRs were due to Dorzolamide + Timolol eye drops followed by Prostaglandin analogues. Conclusion: From the present study it is concluded that there are various treatment strategies in the management of Primary Glaucoma. ADRs to Ocular hypotensive agent is not uncommon and have major impact on Glaucoma treatment. Ideal combination that can lower IOP with minimal adverse effect is preferable.
Authors and Affiliations
Dr. Bhuvaneshwari, Dr. Anusha Rani MV, Dr. P. Venkataratnam
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