EAT AN ORANGE TO KEEP ANXIETY AT LONG RANGE
Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2012, Vol 3, Issue 10
Abstract
Orange fruit (citrus sinensis) is a favorite fruit of all sections of the society, particularly among patients suffering from different ailments for its nutritional and medicinal properties. This study was undertaken to test the efficacy of orange juice in the management of anxiety. A total of 72 mice divided in 12 groups were employed in this study. Orange juice (2.5%, 5%, 7.5%, 10% v/v) was administered orally to mice with the help of an oral feeding needle. Elevated plus maze and light - dark model served as behavioral models in this study. Peripheral cholesterol, reduced glutathione and thiobarbituric acid levels were estimated before and after administration of orange juice. Citrus sinensis significantly increased the time spent by mice in open arm in elevated plus maze test. Furthermore, there was enhancement in the time spent by mice in lit compartment of the light - dark model. Orange juice significantly (P<0.01) increased the GSH levels of brain. On the other hand, orange juice significantly (P<0.01) decreased the TBARS and cholesterol levels. All these findings, when combined together reflect the anti-anxiety potential of orange juice.
Authors and Affiliations
Milind Parle , Dev Chaturvedi
Keywords
Related Articles
- EP ID EP135395
- DOI -
- Views 78
- Downloads 0
PHYSICO CHEMICAL ANALYSIS OF PANCHAVAKTRA RAS: A HERBO-MINERAL FORMULATION
Panchavaktra Ras is a rational combination of Rasadravyas and Kasthaushadhis prescribed in the management of Amavata. Panchavaktra rasa has been taken into consideration for its Pharmaceutical standardization through Sta...
ANTIBACTERIAL POTENTIAL OF GLORY LILY, GLORIOSA SUPERBA LINN.
The successive Soxhlet extract of Gloriosa superba, L. (Liliaceae) was extracted using acetone, dichloromethane, chloroform and methanol in ascending order of the polarity. The extracts were investigated for their antiba...
A STUDY OF SELF MEDICATION AMONG THE PEOPLE OF BHOPAL REGION MADHYA PRADESH, INDIA
The aim of study is to gather information on extent of self medication practice. The outcome of the study will provide data regarding reasons, public awareness and safety aspects of self medication in Bhopal city. It was...
A NOVEL VALIDATED RP-HPLC METHOD FOR THE DETERMINATION OF ITOPRIDE HYDROCHLORIDE IN BULK AND PHARMACEUTICAL TABLET DOSAGE FORMS
A simple, specific, accurate, rapid, inexpensive isocratic Reversed Phase-High Performance Liquid Chromatography (RP-HPLC) method was developed and validated for the quantitative determination of Itopride HCl in pharmace...
PATTERN OF PHARMACEUTICAL DRUG POISONING IN SOUTH INDIAN TERTIARY CARE HOSPITALS
Objective was to study the pattern of pharmaceutical drug poisoning (PDP) in four South Indian tertiary care hospitals. Prospective, observational study included patients admitted to emergency departments of four tertiar...