Effect of Age and Diabetic Duration on Levels of Microalbuminuria among Type 2 Diabetic Patients
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2018, Vol 6, Issue 12
Abstract
Abstract: Out of 10, one adult will encompass diabetes by 2030; facts indicate that the figure of persons inhabiting with this disorder is anticipated to go up from 366 million in 2011 to 552 million by 2030, if no critical act is undertaken. During the first 5 years of diabetes, thickening of the glomerular basement membrane, glomerular hypertrophy, and mesangial volume expansion occur as the GFR returns to normal. After 5–10 years of type 1diabetes, nearly 40% of individuals begin to excrete small amounts of albumin in the urine.1 Microalbuminuria is present in 20-30% of all patients with type 2 diabetes mellitus, and is especially common in those with hypertension, endothelial dysfunction and other features of insulin resistance. Thus, the present study was conduct to estimate microalbuminuria among type 2 diabetes mellitus and to correlate age and diabetic duration with the levels of microalbuminuria among such patients. The case-control study was conducted in the Department of Biochemistry, Maharishi Markandeshwar Institute of Medical Sciences and Research, Mullana (Ambala), India by taking fifty diagnosed cases of type 2 diabetes mellitus and fifty age and sex matched apparently healthy controls. It was found that the prevalence of microalbuminuria was 52 %. In type 2 diabetic patients, mean FPG and microalbuminuria were higher as compared with healthy controls. Thus, there was significant difference (p<0.001) in levels of FPG and microalbuminuria. Further, there was strong correlation between microalbuminuria and glycemic control. Also, there was significant correlation of microalbuminuria with age and the duration of diabetes in type 2 diabetic patients. With the increase in duration of diabetes, there was significant progression of microalbuminuria to macroalbuminuria (>300 mg/day). Hence, it was concluded that the early determination of microalbuminuria should be implemented in clinical practice for overall risk evaluation, at least in diabetic patients.
Authors and Affiliations
Dr. Jai Prakash Bhartiya, Narendra Kumar Sah, Dr. Harpreet Kaur Walia, Dr. Kamaljit Singh
Keywords
Related Articles
- EP ID EP480085
- DOI -
- Views 56
- Downloads 0
Measurement of Patient Dose in Vascular Intervential Radiography
Cardiac catheterizations have contributed greatly to the treatment of heart diseases. However the radiation exposure to the patient is significantly higher compared with other radiological examinations. The objectives of...
Prospective Study of Trichomonas vaginalis Infection
A total of 60 vaginal swab samples from women were collected and examined at Kut Hospital for Women and Children in Wasit province for the period of October 2013 to the end of January 2014. All women aged (14-53) years o...
Psychological assessment in ICU survivors using DASS-21 scale
Abstract: When patients are admitted in ICU, psychological problem such as depression, anxiety, stress, etc. are commonly seen and that affects the outcome of the patient. To assess these symptoms we used the DASS-21 (De...
Knowledge and awareness of the radiation safety among the medical students and resident doctors
Abstract: In day to day medical investigations radiations now become a must for the diagnosis. The radiations having most of the health risk for the doctors in constant contact with such procedures. During the learning p...
Quantitative and Qualitative Assessment of Phenomenology of OCD at Saraswathi Institute of Medical Sciences, Hapur
Abstract: The study was performed from January 2017 to May 2018 Outdoor & Indoor patient, Department of psychiatry, Saraswathi Institute of Medical Sciences, Hapur, Uttar Pradesh, The study had 50 patients of OCD, 50 car...