Effect of Azadirachta indica A. Juss (Meliaceae) Seed Oil and Extract Against Culex quinquefasciatus Say (Diptera: Culicidae) Larval Susceptibility of Indian Subcontinent
Journal Title: Macedonian Journal of Medical Sciences (MJMS) - Year 2011, Vol 4, Issue 1
Abstract
Background. Development of resistance to chemical pesticides among the mosquito vectors leads researchers to investigate the potential mosquito control efficacy of various plant extracts. Aim. To assess the larvicidal activity of neem (Azadirachta indica A. Juss; Meliaceae) seed extract and oil against Culex quinquefasciatus Say (Family: Culicidae). Materials and Methods. In order to determine the median lethal concentration (LC50), following probit analysis the fourth instar larvae of C. quinquefasciatus were exposed to A. indica seed extract and oil in different concentrations ranging from 2 to 64 μg/ml, and larval mortality was observed for each concentration after 24 hours of treatment. The median lethal time (LT50) values for a single concentration (2 x LC50) of oil and extract were determined based upon probit analysis. Results. The 100 % larval mortality was observed due to both A. indica seed oil and extract at concentrations 32 μg/ml and 64 μg/ml, respectively. The A. indica oil and extract had LC50 values 8.041 and 15.495 μg/ml, respectively, and the LT50 values were 8.328 and 15.322 min, respectively. Conclusion. The A. indica seed oil and extract showed excellent larvicidal activity against C. quinquefasciatus, and thus the products can be used effectively as indigenous mosquito control agents, alternative to conventional chemical mosquito larvicides.
Authors and Affiliations
Shyamapada Mandal| Department of Microbiology, Bacteriology and Serology Unit, Calcutta School of Tropical Medicine, C. R. Avenue, Kolkata-700 073, India
Keywords
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- EP ID EP8778
- DOI 10.3889/MJMS.1857-5773.2011.0127
- Views 331
- Downloads 17
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