EFFECT OF BLOOD DONATION ON LIPID PROFILE IN HEALTHY VOLUNTEERS- A SHORT-TERM PILOT STUDY
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 33
Abstract
BACKGROUND It is a known fact that giving the blood helps the other in more than one way. One pint of blood given by the donor can save the lives of as many as three individuals. The aim of the study was to estimate the effect of lipid profile after 7th, 30th and 90th days of blood donation. MATERIALS AND METHODS This is a descriptive study. 30 healthy volunteers were included in the study without any major illness. Total cholesterol was estimated by CHOD-POD method. HDLc was estimated by phosphotungstic acid method. TG was estimated by GPO-POD method. LDLc was estimated by using formula of Friedewald et al. RESULTS All the parameters of lipid profile, e.g. TC, LDL, VLDL except HDL was highly significantly decreased (p < 0.001) after 7th and the effects continued till 30th day after blood donation, which was highly significantly decreased (p < 0.05, HDL). It was significantly increased (p < 0.05) after 7th and 30th day of blood donation. At 90th day, all values were normalised. CONCLUSION The act of blood donation has favourable hypolipidaemic effect even in normal healthy volunteers, which starts as early as 7 days and gets normalised by 90 days with continued raised levels of HDL.
Authors and Affiliations
Sunita Avinash Turankar, Avinash Vikram Turankar, Seema Vaidya, Saurabh Balpande
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