Effect of Calcium and Vitamin D Supplementation in Patients with Fracture Nonunions
Journal Title: Journal of Pakistan Orthopaedic Association - Year 2013, Vol 25, Issue 03
Abstract
To study the effects of calcium and vitamin D supplementation in cases of fracture nonunion. Study design: Non-randomized intervention study. Place and duration of study: This study was carried out at Combined Military Hospital Gujranwala Cantonment, from October 2010 to October 2011. Methodology: 14 patients were included. Serum calcium, vitamin D and parathormone (PTH) levels were determined in all of these patients. The patients were divided into 2 main groups. Group 1 was medical where only calcium and vitamin D supplementation was done. Group 2 was surgical which was again divided into two subgroups. In sub-group (A) surgery was supplemented with calcium and vitamin D administration, and second sub-group (B) underwent surgery with no supplementation. Tab Qalsan, 1 OD and tab Bone One 0.5ug was administered as calcium and vitamin D supplementation. Follow up of the cases was done on monthly basis. Calcium and vitamin D supplementation was continued till union of fractures. Results: In this study males were 85.71%. Mean age was 37.71 years. The mean duration from injury to presentation with nonunion in our study was 11.4 months. Out of 14 patients, 5 cases were managed with calcium and vitamin D3 therapy only. 2 cases underwent operative intervention with calcium and vitamin D3 therapy. 7 cases underwent operative intervention without calcium and vitamin D3 administration. 2 patients had low serum calcium, 6 had low serum vitamin D and 1 had low serum parathyroid hormone level. 95% confidence interval for having a metabolic or endocrine abnormality for patients with nonunion was 26.8% to 73.2% by Adjusted Wald Method. All of the patients achieved bony union. The mean time for union was 6. 4 months. Conclusion: Vitamin D deficiency was detected in 6 of our patients suffering with long bones nonunion. With oral calcium and vitamin D replenishment, union was achieved. This shows that metabolic supplements do have a role in union of fractures in addition to appropriate surgical intervention.
Authors and Affiliations
LT COL DR SYED FARAZ ANWAR, MAJOR DR SAJDA SHAHEEN, COL M SUHAIL AMIN
Keywords
Related Articles
- EP ID EP742647
- DOI -
- Views 34
- Downloads 0
Comparison of Closed Versus Open Interlocking Nail Femur: A Retrospective Cohort Study in a Tertiary Care Hospital
Objective: To compare the results of closed interlocking nail shaft of femur versus open interlocking nail in terms of union, non-union and infection rate. Methods: We conducted this retrospective Cohort study in Depa...
Indications and Complications of Implant Removal from Extremities in Adult Orthopaedic Patients – A Retrospective Study in a Tertiary Care Hospital.
Objectives: To determine the indications and complications of implant removal from extremities in adult Orthopaedic patients in Abbasi Shaheed Hospital Karachi. Methods: This retrospective Cohort study was conducted i...
Knowledge and Awareness of Osteoporosis in Female Population of Hyderabad, Pakistan.
Objectives: To assess the knowledge and awareness of Osteoporosis in female population of Hyderabad Pakistan. Methods: This cross-sectional study was conducted from 10th April 2019 to 10th June 2019 in Muhammad Medica...
A Radiological Study on Cervical Rib and Associated Chest Wall Anomalies
Objective: To reveal the association of cervical rib with chest wall anomalies. Methods: Observational study conducted at the private radiology clinics Rawalpindi & Islamabad from January 2015 to December 2017, which...
The Association of Disease Duration & Patient Activity Loss with Incident Depressive Symptoms in Adult Orthopedic Trauma Patients.
Objective: The objective of this study was to find the association of disease duration & patient activity loss with the incident depressive symptoms in adult orthopedic trauma patients in population of DIKhan division, P...