Effect of Cholecystectomy on Serum Lipid Profile in Gallstone Patients: A Comparative Study
Journal Title: International Journal of Medical Research Professionals - Year 2018, Vol 4, Issue 2
Abstract
Background: Gallstones represent the calcified aggregations of the bile (digestive fluid) that can form inside the gallbladder. A positive association of occurrence of gallstone diseases and lower levels of high-density lipoprotein cholesterol (HDL-c) and high triglycerides has also been demonstrated in the past literature.7 In the recent reports, the topic of research has been the association of cholesterol gallstones and means serum lipid profile. Hence; we planned the present study to assess the correlation between the serum lipid profile and occurrence of cholesterol gallstones. Materials & Methods: We planned the present study evaluate of serum lipid profile in gallstone patients. A total of 50 gallstone patients and 50 normal healthy controls were included in the present study. Complete demographic details of all the patients along with detailed history were obtained. Haematological investigations were performed in all patients before the starting of the surgery. Fasting serum lipid profile was obtained in all the patients. All the patients underwent laparoscopic cholecystectomy under the hands of skilled and experienced surgeons. Blood samples were taken thrice in all the patients. First sample was taken preoperatively, second sample was taken at 72 hours postoperatively and the third sample was taken at 20 days postoperatively. All the samples were subjected to analysis by Autoanalyzer machine. All the results were analyzed by SPSS software. Results: Significant results were obtained while comparing the preoperative lipid profile in between the study group and the control group. Significant results were obtained while comparing the lipid profile pre-operatively and post- operatively on third day. A further significant decrease in the lipid profile was seen at twenty day time. Conclusion: Consideration of gallstones as a marker of metabolic pathology should be done and, therefore, treatment should be carried accordingly.
Authors and Affiliations
Yogendra Kumar, Neelkamal Gola, Vinod Kapoor
Keywords
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- EP ID EP538108
- DOI 10.21276/ijmrp.2018.4.2.024
- Views 80
- Downloads 0
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