Effect of cold pressor test on blood pressure in normotensives and hypertensives

Journal Title: National Journal of Physiology, Pharmacy and Pharmacology - Year 2018, Vol 8, Issue 2

Abstract

Background: Hypertension is an important worldwide public health challenge because of its high frequency and concomitant risks of cardiovascular and kidney disease. The cold pressor test (CPT) as a tool to measure cardiovascular reactivity, specifically blood pressure (BP) changes, in response to stress. Aims and Objectives: The aim of the study is to see the effect CPT on hypertensives and age and gender-matched normotensive (NT) individuals. Materials and Methods: The study was carried out in 60 individuals aged between 30 and 60 years consisting of 30 known cases of hypertension and 30 age and gender-matched normotensive (NT) from outpatient department of Mc Gann Hospital, Shimoga. Keeping CPT as the stimulus, the response was recorded in all the individuals and they were divided into normoreactors and hyperreactors. Statistical analysis was done using SPSS 21. Results: Hypertensives showed a significantly higher increase in systolic and diastolic BP and greater number of hyperreactors (P > 0.01) when compared to the NT for the CPT. Conclusion: CPT has been used for the diagnosis of cardiovascular reactivity in NT and hypertensive individuals and the responses to CPT may help identify NT candidates at future risk of suffering from hypertensive disease. It also helps implement early preventive measures to halt the progression to sustained hypertension developing at a future date.

Authors and Affiliations

Mythri G, Shireen Swaliha Quadri

Keywords

Related Articles

Evaluation of analgesic effect of Gentamicin in thermally induced pain models in rats and mice

Background: Evidence has accumulated for the involvement of calcium ions in nociception and N-type voltage-dependent calcium channels being critical for pain transduction and modulation. N-type calcium channel blockers r...

Evaluation of anticonvulsant activity of ethanolic extract of leaves of Ocimum sanctum (tulsi) in albino rats

Background: Epilepsy is a chronic neurological disorder. Ocimum sanctum (OS) (tulsi) has analgesic, anticancer, antiasthmatic, antidiabetic, antifertility, hepatoprotective, hypotensive, hypolipidemic, anti-inflammatory,...

Impact of horizontal and vertical integration: Learning and perception in first-year medical students

Background: Medical field and its curriculum is dynamic in nature which keeps on adding huge data each year, thus overburdening the students with content information. Most of the colleges in India teach subject in isolat...

HSV-induced hepatitis in pregnancy - A rare case report

Hepatitis is mostly occurred by alcohol, drugs, or virus. Herpes simplex virus (HSV) hepatitis is rare and accounts for only 1% of all acute liver failures, but it is a fatal complication. Pregnant women are more vulnera...

Comparative analysis of sympathetic nervous system activity in pre‑menopausal and post-menopausal women

Background: Post-menopausal women suffer from various complications like autonomic dysfunction which predisposes them to cardiovascular morbidity. Decline in estrogen levels after menopause is associated with increased c...

Download PDF file
  • EP ID EP451649
  • DOI 10.5455/njppp.2018.8.0010728417082017001
  • Views 70
  • Downloads 0

How To Cite

Mythri G, Shireen Swaliha Quadri (2018). Effect of cold pressor test on blood pressure in normotensives and hypertensives. National Journal of Physiology, Pharmacy and Pharmacology, 8(2), 177-181. https://europub.co.uk./articles/-A-451649