Effect of Duration of Diabetes on Heart Rate Variability in Type 2 Diabetes Mellitus
Journal Title: International Journal of Current Research and Review - Year 2018, Vol 10, Issue 6
Abstract
Introduction: Diabetes is a metabolic disorder with debilitating complications which affects several million people worldwide. Cardiac Autonomic Neuropathy (CAN) is the most common chronic complication of type 2 diabetes mellitus (T2DM), which is concealed for long period of disease. Heart rate variability (HRV) test is the simple and sensitive test for CAN. Diagnosing CAN at subclinical stage and knowing the correlation of HRV with duration of diabetes can help to prevent the morbidity and mortality because of this neuropathy. Objective: This study aims to determine the correlation of HRV with duration of diabetes in type 2 diabetes mellitus. Materials and Methods: This cross sectional study was conducted in Department of Physiology, in collaboration with Rajeev Gandhi Centre for Diabetes and Endocrinology on patients of T2DM attending Diabetes clinic in Jawaharlal Nehru Medical college hospital (JNMCH), AMU, Aligarh, from 2014 to 2016 after approval from the ethical committee of J. N. Medical College. Total 90 subjects were taken, among whom 60 subjects were diagnosed cases of T2DM, which were divided in two groups on the basis of duration of diabetes. Rest 30 subjects were non diabetic control group. For CAN heart rate variability test was done. Statistical analysis was performed using SPSS version 21.0. Results: In shorter duration Diabetes (3.31 ± 1.72 years T2DM), significant (p value<0.05) negative correlation was seen between duration of diabetes and pNN50, RMSSD, HF power and LF/HF ratio, while in longer duration of Diabetes (12 ± 4.42 years T2DM), there was significant (p value<0.05) negative correlation between duration of diabetes and all four HRV parameters, namely, pNN50, RMSSD, HF power, LF power, LF/HF ratio. Conclusion: Chronic hyperglycemia in diabetes leads to the degeneration and damage of autonomic nerves.
Authors and Affiliations
Amina Sultan Zaidi
Keywords
Related Articles
- EP ID EP542249
- DOI 10.7324/IJCRR.2018.1068
- Views 125
- Downloads 0
Diabetic Patients ‘Perception of Their Relationship with Family Caregiver and Health-Care Providers: A Qualitative Study in the Diabetes Centre of the National Public Health Institute of Côte d’Ivoire
Objective: This study aimed to investigate diabetic patients’ perceptions of their relationship with healthcare providers and family caregivers. Methods: This qualitative study using semi-structured questionnaires was pe...
Post Lecture Multiple Choice Questions (MCQs) Test Improves the Performance of Students
Aim: To study whether post lecture MCQs tests improves the performance of students.
A Review on Quality of Life in Cancer Patients: An Indian Scenario
Cancer is a major public health concern among million of people worldwide and claims thousands of life. The main aim of this review article was to assess the Quality of life (QOL) in Indian cancer patients. QOL is a vita...
Diversity of the Family Leguminosae in Koch Bihar District, West Bengal
Introduction: Legume - a fascinating group of flowering plants belongs to the family Leguminosae or Fabaceae is deserve special attention as they play vital role both in human welfare as well as in ecological aspect. The...
Profile of Metal Accumulation in Aquatic Macrophytes
Industrial development coupled with population growth has resulted in the over exploitation of natural resources. Life support systems viz; water, air and soil are thus getting exposed to an array of pollutants especiall...