Effect of Honey in Radiation Induced Mucositis in Head and Neck Cancer

Journal Title: International Journal of Contemporary Medical Research - Year 2016, Vol 3, Issue 1

Abstract

Introduction: Mucositis is a common side effect of chemo radiotherapy to the head and neck region. It compromises patient’s health and quality of life. Standard treatment is not available at present. Care is limited to symptom control. Honey has anti-bacterial and anti-inflammatory properties. It is naturally available, cheap, and ubiquitous. Hence to know the effect of honey in radiation induced mucositis. Materials & methods: 56 cancer patients receiving concurrent chemoradiotherapy to head and neck region were recruited in this study from October 2012 to august 2014. Study group consisted 27 patients and control group consisted 29 patients. Study group patients received topical application of honey collected from CAROM plant along with chemo radiotherapy and control group patients received only chemo radiotherapy. All patients were assessed twice a week for the onset and severity of mucositis. Both study and control group patients were advised to take plenty of oral fluids, supplementation with high protein diet and oro dental care. Results: 15 (55.6%) patients in study group developed mucositis at 13th fraction whereas 15(51.7%) patients in control group developed mucositis at 10th fraction indicating that honey postpones the onset of radiation induced mucositis. The severity of radiation induced mucositis at every assessment showed statistically significant difference between study group and control group. This clearly showed control group patients were with higher grades of mucositis than study group patients. Conclusion: This prospective interventional study found the usefulness of topical application of honey in reducing the onset and severity of radiation induced mucositis in patients receiving chemo radiation to head and neck cancers.

Authors and Affiliations

John Winkle Medida, Bala Sankar Ramavath, Joseph Benjamin Gandi

Keywords

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  • EP ID EP424982
  • DOI -
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How To Cite

John Winkle Medida, Bala Sankar Ramavath, Joseph Benjamin Gandi (2016). Effect of Honey in Radiation Induced Mucositis in Head and Neck Cancer. International Journal of Contemporary Medical Research, 3(1), 108-113. https://europub.co.uk./articles/-A-424982