Effect of MSG as a food additive on organo-somatic indicator and sperms abnormalities in adult male mice
Journal Title: Scientific Journal of Medical Research - Year 2017, Vol 1, Issue 2
Abstract
Objective: Monosodium glutamate (MSG) is the sodium salt of the non-essential amino acid glutamic acid. It is naturally present in the organs and tissues of the human body, such as in our digestive system, brain, milk, and blood. The aim of this project study was to investigate the effect of MSG that is used as a food additive on organo-somatic index and on sperm abnormalities. Methods: In the present project, MSG was given orally at a dose of 4 mg/g body weight dissolved in drinking water and given to three groups of male mice for different periods 7, 14, and 21 days beside to control group which treated with drinking water only for 7 days orally. Each group contained five animals to study the organo-somatic indicator and sperm abnormalities assay. Results: The results show that there were no significant differences between the control group with the treated groups for 14 and 21 days, respectively, in the liver, kidney, and testes. While there was a significant difference between control group compared with the treated group for 7 days in all the organs (liver, kidney, and testes) in organo-somatic index. A significant increase in the weight of the mice was observed after the administration of MSG for 7 days with no change in the liver, kidney and testes. This led to decrease the organo-somatic index. In sperm abnormalities study, the results showed a significant difference, such as an increase in the number of abnormal sperm in treating animals for 1, 2, and 3 weeks compared with the control group. The results showed a different types of sperm abnormalities as headless, tailless, hook less, and abnormal sperm head. There was a statistically significant reduction in the normal sperms of the mice that received MSG for 7, 14, and 21 days compared with the control group. Conclusion: A significant increase in the weight of the mice was observed after the administration of MSG, and there was a significant reduction in the normal sperms of the mice that received MSG.
Authors and Affiliations
Radhiah Najm Abd
Keywords
Related Articles
- EP ID EP204558
- DOI -
- Views 188
- Downloads 0
Prevalence of Cysticercus tenuicollis in slaughtered sheep and goats by season, sex, age, at Karbala abattoir, Iraq
Objective: The aim of this study is determine the prevalence of Cysticercus tenuicollis in sheep and goats at abattoir in Karbala , Iraq. Methods: The current study was conducted for six months from July to December 2017...
Phenetic and Phylogenetic Analysis of Kocuria palustris and Kocuria rhizophila Strains isolated from Healthy and Thalassemia Persons
Objective: The normal habitat of Kocuria palustris and K. rhizophila include mammalian skin, soil and rhizoplane. The aim of this study is to find the relatedness among several strains of K. palustris and K. rhizophila...
THE BETA-THALASSEMIA
The thalassemias are hereditary anemias caused by mutations that affect the synthesis of the globin, the protein component of the hemoglobin. Thalassemias produce massive public health problems in many parts of the world...
Estimating the sensitivity and Specificity of Reverse transcriptase polymerase chain reaction (RT-PCR) with Rota virus latex agglutination test (Virogen Rotatest) in calves suffering from diarrhea in Karbala province
Objective: The aim of this study was to estimate the sensitivity and specificity of reverse transcriptase polymerase chain reaction (RT-PCR) in the detection of Rotaviral diarrhea in calves, and to compare with Rota viru...
Evaluation of immunization protocol in mice injected with Whole Cell Fraction antigen of C. albicans isolated from vaginal infections
Objective: The present study aimed to isolation and identification of C. albicans from women infected with vaginal candidiasis, then Preparation of whole cell fraction (WCF) antigen and testing immunization efficiency b...