Effect of Radiotherapy on Antioxidant Vitamin E in Patients with Carcinoma Uterine Cervix- a Pilot Study
Journal Title: Journal of Oncology and Cancer Research - Year 2017, Vol 1, Issue 1
Abstract
Vitamin E, a fat-soluble antioxidant, stops the production of Reactive Oxygen Species (ROS) during the process of fat oxidation. It is used to prevent and repair normal tissue damage and to increase the susceptibility of tumor tissue to radiation treatment. In this study, we analyzed the serum antioxidant vitamin E, before, midway and at the completion of radiotherapy and monthly follow-up for six months and monitored the respective responses to radiotherapy in 33 patients histopathologically confirmed of carcinoma uterine cervix. Statistically significant low levels of serum vitamin E were observed before radiotherapy. Results indicate that decreased antioxidant vitamin E depicts the progression of carcinoma uterine cervix disease. The serum vitamin E analysis as per the stage of the disease is also in agreement with this and at six months follow-up, the mean serum vitamin E levels were found to be higher in IIA, IIB and III stages of carcinoma uterine cervix.
Authors and Affiliations
Arun Chougule, Bhawani Kochar, Mary Joan
Keywords
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- EP ID EP249308
- DOI 10.28967/jocr.2017.01.17001
- Views 117
- Downloads 0
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