Effect of radiotherapy on cognitive functioning in nasopharyngeal carcinoma
Journal Title: Journal of Medical and Scientific Research - Year 2015, Vol 3, Issue 3
Abstract
Background: Radiotherapy is used in the treatment of nasopharyngeal carcinoma (NPC). The temporal lobes are at risk because they lie directly in the path of radiation beams; hence the effect of radiotherapy on cognitive functioning is a major concern. Aims: To investigate the effect of radiotherapy on cognitive functioning in nasophyingeal carcinoma patients. Materials & methods: A battery of neuropsychological tests consisting of attention, memory & learning and visuospatial functions was done on 20 patients before and after radiation therapy. Also computerized tomography (CT) was done in all cases. The results showed significant impairment in attention (p=0.0001), verbal fluency (p=0.05), visuospatial functions (p=0.005), and learning & memory. Conclusions: Radiotherapy for nasopharyngeal carcinoma shows significant decline on cognitive functioning.
Authors and Affiliations
Shanmukhi S, Thomas PN
Keywords
Related Articles
- EP ID EP606834
- DOI 10.17727/JMSR.2015/3-022
- Views 74
- Downloads 0
Role of traditional medicines in the management of cancer
Context: Increasing numbers of cancer patients are looking towards traditional medicines (TM) in an effort to sustain tumour remission or halt the metastasis. TM such as Chinese Traditional Medicines, Ayurveda and Unani...
Skull radiographs as a guide for diagnosing systemic disorders (Pictorial Atlas)
No Abstract is available for this article
Schwannoma of intermediate supraclavicular nerve: Case report
Schwannoma of supraclavicular nerve is very rare tumour occurring in head and neck region. This case is reported as a rare case of intermediate supraclavicular nerve schwannoma. A 48-year-old female patient presented to...
Foramen magnum decompression and arthrodesis in a septic, neuropathic elbow: A case report
Neuropathic arthropathy is a chronic progressive degenerative joint disorder associated with abnormal sensory innervation of a joint. This article presents a patient of a forty seven year old man who came with a swollen,...
Reconstruction of lateral humerus condylar defect using tricortical iliac crest graft: A case report
Comminuted fractures of distal humerus are most commonly the result of high energy trauma. There is an extensive damage to soft tissues along with articular cartilage fragmentation and many a time associated with bone lo...