Effect of Tender Coconut Water on Blood Lipid Levels in High Fat Diet Fed Male Rats
Journal Title: Journal of Krishna Institute of Medical Sciences University - Year 2017, Vol 6, Issue 2
Abstract
Background: Dyslipidemia is a lipid metabolic disorder characterized by an increased levels of Triglycerides (TG), Total Cholesterol (TC), Low-Density Lipoprotein (LDL)cholesterol, and decreased Hight-Density Lipoprotein (HDL) cholesterol levels. Aim and Objectives: To investigate the effect of the administration of tender coconut water on blood lipid levels in male wistar rats. Material and Methods: Twenty four male wistar rats were randomly divided into four group of six animals each. Group K1 served as control, Group K2 was fed quail egg yolk (1g/rat/day). Group K3 was given coconut water (8 ml/rat/day) orally. Group K4 was given simvastatin (0.18 mg /rat /day) orally for 21 days. Results: that increased levels of TC, LDL and TG with decreased level of HDL were shown in group K2 compared with group K1. Decreased levels of TC, LDL and TG levels were observed significantly in both groups K3 and K4 than K2. Administration of 8ml coconut (200g/kg b w for 21 days) could lower TC, LDL and TG levels with an increased HDL level (p <0.05).Conclusion: The administration of tender coconut water has shown lower total cholesterol, LDL cholesterol and triglyserides levels and increase HDL serum levels in male wistar rats fed a high fat diet.
Authors and Affiliations
Siti Thomas Z, Danis Pertiwi, Bagus SA, Brillian Jelita E M, Alfiza NS
Keywords
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