EFFECTIVENESS AND SAFETY OF BACILLUS CALMETTE-GUERIN (BCG) VACCINE IN WARTS
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2017, Vol 6, Issue 94
Abstract
BACKGROUND Viral warts are common dermatological diseases caused by human papilloma virus. Immunotherapy has now become the therapeutic modality for treatment of warts. We conducted this study to assess the efficacy and safety of intralesional BCG Vaccine for treatment of warts. MATERIALS AND METHODS We have selected 30 patients belonging to age group 10 to 45 years of both the sexes having multiple warts predominantly common warts and palmoplantar warts. Intralesional BCG vaccine 0.1 mL was injected into single wart at a time, with prior Mantoux test. Thereafter, remaining lesions were injected with 0.1 mL BCG vaccine, one lesion at every session with 2 weeks interval for a period of 3 months. Treatment was stopped if there was no response after 5 injections. Study Design- Uncontrolled clinical trial. Study Setting- Patients attended in OPD of DVL Department in KGH (affiliated to Andhra Medical College), Visakhapatnam, AP, India. RESULTS Out of 30 patients, 26 patients (86.6%) had complete resolution of their warts both at the injected and the distant sites. 2 patients (6%) had recurrence. Treatment was well tolerated and the side effects were reversible. CONCLUSION Our study results showed the efficacy of BCG vaccine for the treatment of warts comparable with previous studies. It has shown high cure rate at injected as well as distant sites with lower recurrence rates. The treatment is cost effective with minimal treatable side effects.
Authors and Affiliations
Chenna Subhashini, Mohan Rao T. S, Swetha Naidu K, Anila Sunandini P, Guru Prasad P, Rupa Ramani, Shaik Asha, Chankravarthy S. N. R
Keywords
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- EP ID EP280006
- DOI 10.14260/jemds/2017/1497
- Views 96
- Downloads 0
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