Effectiveness of predicting outcome in septic shock in critically ill children by assessing serum lactate levels
Journal Title: Pediatric Review: International Journal of Pediatric Research - Year 2016, Vol 3, Issue 1
Abstract
Background and Aims: Hyperlactatemia at the time of admission is a documented risk factor for mortality in critically ill adult patients. However, the significance of lactate measurement at admission for mortality in critically ill children remains uncertain. This study evaluated the predictive value of blood lactate levels at the time of admission and determined the cut-off values for predicting in-hospital mortality in the critically ill children. Materials and Methods: A total of 60 children with diagnosis of sepsis admitted to PICU of a tertiary care hospital were included in the study. PRISM III score and demographic characteristics of all children were recorded. Serum lactate levels were measured at 0-3, 12 and 24 h of PICU admission. The outcome like survival or death was correlated with serum lactate levels. Results: Septic shock was the most common type of shock and had highest mortality. Lactate levels were significantly higher in non survivors in comparison to survivors. A lactate value of more than 5 mmol/l at 0-3, 12 and 24h of PICU admission had increased mortality. Conclusions: A high blood lactate level at admission is independently associated with higher in-hospital mortality in the critically ill children.
Authors and Affiliations
Jasashree Choudhury, Sidharth Sraban Routray
Keywords
Related Articles
- EP ID EP223126
- DOI 10.17511
- Views 204
- Downloads 0
Physical activity, sedentary behaviours and eating habits among school children in kerala
Background: World Health Organization refers obesity as a global epidemic including children and adults. Low levels of physical activity, TV watching, and unhealthy food habits are risk factors for overweight and obesity...
Outcome analysis of intussusception in fifty children at a tertiary centre in Mumbai
Background: Intussusception is a common cause of obstruction in Paediatric patients. Recognizing and treating this condition rapidly is important to prevent potentially fatal complications. Methods: Fifty consecutive pat...
Bubble CPAP for Respiratory distress in Neonate
Respiratory Distress Syndrome is a major contributor towards Neonatal Mortality Rate. Effective ventilation strategies which are safe, effective and low cost are required to manage neonates with Respiratory Distress Synd...
Impact of media on sleep quality of adolescents
Introduction: Sleep disturbanceis an important risk factor for the development of depression during adolescence. Excessive electronic media usage at night was a risk factor for adolescents’ sleep disturbance. As late sle...
Pattern of Early Neonatal Morbidities in Moderate and Late Pre-terms
Objective: The present study is an attempt to analyze the data on the pattern of early neonatal morbidities among moderate and late preterm infants of 32 full weeks of gestation to 36+6 weeks’ gestational age in a tertia...