Effects of Eruca sativa Leaves Extracts on Testes, Fertility Potential and Testosterone Concentration in Male Rats
Journal Title: Annual Research & Review in Biology - Year 2017, Vol 16, Issue 6
Abstract
Background: Eruca sativa (E.S.) is a worldwide herbaceous plant usually used for salad preparations and in traditional medicine for their therapeutic properties. Aims: This study aimed to determine the effect of ethanolic extract of Eruca sativa leaves (E.S.) on testosterone levels, and histological changes of testes. Methodology: Fourteen albino male rats were divided into two groups: Group A, rats served as controls. Group B, the rats dosed orally with 500 mg kg-1 of extract daily for 4 weeks. Student’s t-test was used to compare the mean values of experimental group and control. Results: The results showed that final body weight was significantly lower (P<0.05) than in the control. A significant increase (P<0.05) of testes weight was observed as compared with control. Significant differences (P<0.05) were also found in the mean concentration of testosterone between the experimental group and the control (6.294 ng/ml and 3.256 ng/ml, respectively).The dose caused a significant increase (P<0.05) of total protein and total cholesterol value, compared to the control. On the other hand, a significant reduction (P< 0.05) of triglycerides was observed. The histological study showed a decrease in the interstitial space, an increase in the diameter of seminiferous tubules, spermatid and leydig cells compared with the control. Conclusion: Ethanolic extract of E.S. leaves could increase fertility potential and testosterone concentration in male rats. This plant seems to reduce serum cholesterol levels with some alterations in the structure and ultrastructure of the testes when this dose (500 mg kg-1) has used.
Authors and Affiliations
Maisa “Mohammad Amin” Al-Qudah
Keywords
Related Articles
- EP ID EP313457
- DOI 10.9734/ARRB/2017/36016
- Views 93
- Downloads 0
Comparison of Serum Transaminases and CD4 Counts in HIV Patients on ART Regimens Containing Zidovudine versus Stavudine
Introduction: There has been a significant reduction in the mortality and morbidity associated with AIDS, due to the availability of highly active retroviral therapy (HAART). However adverse drug reactions related to ART...
Bacteriological and Physicochemical Quality of Malabor Hostel Tap Water - University of Calabar, Nigeria
Tap water samples collected from different halls in Malabor hostel were analyzed for total heterotrophic bacteria count, total and faecal coliform counts using direct plating and membrane filtration methods. Total hetero...
Conserving the Hidden Nature: An Overview on Conservation Efforts in United Arab Emirates (UAE)
The aim of the study is to document the threats faced by reptiles with other species in UAE and the conservation efforts done by Barari Forest Management (BFM). The study was conducted by reviewing the factors affecting...
Effects of pH Alteration on the Free Radical Scavenging Ability and Other Antioxidant Properties of Reduced Glutathione
Reduced glutathione (GSH), an endogenous antioxidant ubiquitously distributed in the physiological system has been widely reported to exhibit potent antioxidant properties in vivo and in vitro. However, information regar...
Insecticidal Effects of the Flavonoid-rich Fraction of Leaves Extract of Gamal (Gliricidia sepium) on the Coffee Mealybugs (Planococcus citri Risso.)
Aims: To find out whether flavonoid-rich fractions of aqueous and methanolic extracts of gamal plant leaves, Gliricidia sepium (Jacq.) Kunth ex Walp., can be used for eradicating coffee mealybugs, Planococcus citri Risso...