EFFECTS OF HIGH SPEED RUNNING ON OXIDATIVE STRESS, MUSCLE AND CARDIAC INJURY PARAMETERS
Journal Title: Medicina Sportiva - Year 2014, Vol 18, Issue 1
Abstract
Introduction: Anaerobic exercise may have diverse pathophysiological effects on various organs due to free radical formation.Objective: To assess the effects of sixty meter speed running that was performed for once, on plasma parameters of oxidative stress, skeletal muscle and cardiac damage.Methods: Twenty-two healthy students, aged 18 to 23 years, were included in this study. The subjects were applied a sixty meter speed running test on a dust running track. For biochemical measurements, fasting blood samples were obtained from the subjects both before and after the exercise.Results: Significant increases in lactate dehydrogenase (LDH), aspartate aminotransferase (AST), creatine kinase (CK), CK-MB and CK-MB mass were observed post-exercise (P < 0.001), while cardiac troponin T (cTnT) and myoglobin (Mb) levels were not affected (P > 0.05). Plasma malondialdehyde (MDA) levels significantly increased (P < 0.001) after the exercise but this was not accompanied by changes in erythrocyte superoxide dismutase (SOD) activity (P > 0.05).Conclusions: The results show that when anaerobically trained men run a comparatively short distance sufficient to result in some degree of muscle damage and in plasma indices of lipid peroxidation, but which is insufficient to cause significant alterations in erythrocyte antioxidant status and markers of cardiac markers do occur.
Authors and Affiliations
Emine Siber Namıduru, Ramazan Kocabaş, Mehmet Tarakçıoğlu, Önder Dağlıoğlu
Keywords
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- EP ID EP74232
- DOI 10.5604/17342260.1094783
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