Effects of Inappropriate Acetylsalicylic Acid Use on Non-fatal Bleedings
Journal Title: The Medical Bulletin of Haseki - Year 2019, Vol 57, Issue 4
Abstract
Aim: This study aims to assess of using asetylsalicyclic acid (ASA) on non-fatal major and minor bleeding events in patients with inappropriate, primary and secondary prevention groups. Methods: Nine thousand, six hundred and fifty-one patients were screened within a one-year period. Patients using ASA for primary and secondary prevention were recorded. A total of 736 patients using ASA were divided into three groups as inappropriate, appropriate primary and secondary prevention. Results: One hundred and two (14%) patients were using ASA inappropriately. The duration of ASA use was 82.9±71.3 months. Thirteen (1.8%) major (11 gastrointestinal, one intraocular, one intracranial) and 29 minor (3.9%) bleedings had occurred. Eleven (2.5%) major bleeding events had occurred in secondary prevention group and one (0.5%) in appropriate and one (1%) in inappropriate primary prevention group (p=0.16). Nineteen (4.4%) and 10 (5.1%) minor bleeding events were seen in appropriate and secondary prevention groups, respectively and there was no minor bleeding event occurred in inappropriate primary prevention group (p=0.078). Conclusion: Our study showed that inappropriate ASA use did not increase the risk of non-fatal major and minor bleeding events. It may be reasonable to consider that patients without a history of occlusive vascular disease are less prone to non-fatal bleeding events compared to those with occlusive vascular disease.
Authors and Affiliations
Mustafa Öztürk, Oğuzhan Ekrem Turan
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